Geeky question, is there an explanation for why the Moderna vaccine is stable longer than the Pfizer one in terms of cold storage requirements since they're both mRNA? Or is it just that Moderna tested for longer storage times and Pfizer didn't? Links to long papers welcome!
-
-
Pfizer distribution is going to be much harder and more costly because of its (relatively extreme) refrigeration requirements and shorter shelf-life. This hinders immunization outside hospitals in the US, and makes it much harder in poorer countries. Just looking to learn why/if.
Show this threadThanks. Twitter will use this to make your timeline better. UndoUndo
-
-
-
Pfizer would have to conduct new phase 3 trials if they radically changed the formulation like that, so not going to happen even if Moderna was willing to license the technology...
- Show replies
New conversation -
-
-
Thanks. Twitter will use this to make your timeline better. UndoUndo
-
-
-
they can't change the vaccine.
Thanks. Twitter will use this to make your timeline better. UndoUndo
-
-
-
Even of shared, it'd have to be proven. That is another 6+ months. It'd be similar to lots of drug expiration dates. Aspirin is 5 years. Not because year 6 it changes but because year 6+ were never tested and proven to the FDA.
Thanks. Twitter will use this to make your timeline better. UndoUndo
-
-
-
This Tweet is unavailable.
-
But the CureVac vaccine has similar refrigeration requirements as Moderna's, therefore Acuitas nanoparticles don't explain the difference. https://www.curevac.com/en/covid-19/ pic.twitter.com/m8HFkH2Y4X
End of conversation
-
-
-
I love lipid nanoparticles
Thanks. Twitter will use this to make your timeline better. UndoUndo
-
Loading seems to be taking a while.
Twitter may be over capacity or experiencing a momentary hiccup. Try again or visit Twitter Status for more information.
