Exactly—for both Pfizer and Moderna effects kick in after the first two weeks . See linked chart above. Very encouraging numbers. The companies and presumably the FDA had these numbers in early November. We'd have been almost halfway through a trial.https://twitter.com/OmkarGV/status/1338874594900455427 …
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The concerns are about durability of immunity and also high-risk groups. The former can be resolved with a trial and the latter can be addressed by sticking to the proven—and efficacious beyond almost all early hopes—schedule for those groups.
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Plus, the US is planning to hold off vaccinating half the people *right now*, keeping the second dose for them in the freezer merely in case of production hiccup. At a minimum, can we discuss vaccinating as many a possible now, given a few days off doesn't seems a terrible risk?
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To make sure they cleared the efficacy bar and to ensure durability of immunity. Who knew things would turn out this well? Who wants an under-powered vaccine? We're operating under a lot of uncertainty here and these are the first mass mRNA vaccines.https://twitter.com/EmilSkandul/status/1338876560909152256 …
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why isn't the FDA requiring tracking data for the approved vaccine after 1 dose?
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everybody not in high priority gets one before anyone gets two?
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Important clarification -- 92% efficacy is for between 14-28 days after dose 1. Immediately after the first dose the vaccine hasn't had time to kick in yet.
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so it's very effective even after just one dose?
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What's the reasoning for why they didn't pursue a single dose trial to begin with?
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So... vaccinate as many as possible 1 dose, then wait for production to catch up for the trailer?
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