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zeynep's profile
zeynep tufekci
zeynep tufekci
zeynep tufekci
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@zeynep

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zeynep tufekciVerified account

@zeynep

Complex systems, wicked problems. Society, technology, science and more. @UNC professor. @NYTimes columnist. My newsletter is @insight: http://www.theinsight.org 

floating in a most peculiar way
theinsight.org
Joined August 2009

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    1. Armchair epidemiologist (self-certified)‏ @yellingatwind 10 Dec 2020
      Replying to @zeynep @stgoldst and

      What is stopping a health-care system from deciding on a one dose regimen for now (booster when available) if patients sign waiver? Decision-making under uncertainty is hard but critical in situation like we have now.

      1 reply 0 retweets 0 likes
    2. Stephen Goldstein‏ @stgoldst 10 Dec 2020
      Replying to @yellingatwind @zeynep and

      Does "booster when available" work as well? Or will people have to start over from scratch? That could increase by 1/3 the needed numbers of doses.

      2 replies 0 retweets 1 like
    3. Stephen Goldstein‏ @stgoldst 10 Dec 2020
      Replying to @stgoldst @yellingatwind and

      Vaccine schedules aren't randomly cobbled together. They're based on evidence. The most reliable way to squash the pandemic is to vaccinate consistent with our best evidence for what works.

      2 replies 0 retweets 3 likes
    4. zeynep tufekci‏Verified account @zeynep 10 Dec 2020
      Replying to @stgoldst @yellingatwind and

      Vaccine schedules during a pandemic are not some perfect processes. Besides there is data on both sides. What does it mean to leave hundred million vaccinated, or to delay start to hold off for second shot compared with less durable immunity? That's a societal decision.

      4 replies 0 retweets 1 like
    5. Armchair epidemiologist (self-certified)‏ @yellingatwind 10 Dec 2020
      Replying to @zeynep @stgoldst and

      Armchair epidemiologist (self-certified) Retweeted Armchair epidemiologist (self-certified)

      Agreed. It is just hard for the people who are in charge of these decisions to do that. They are trained from day 1 in "protocols" and the danger of making exceptions. This works great, until you have the one time you should make an exception.https://twitter.com/yellingatwind/status/1336354474806239232?s=20 …

      Armchair epidemiologist (self-certified) added,

      Armchair epidemiologist (self-certified) @yellingatwind
      Hey medical peeps - is there an ethical/practical case for giving twice as many people one dose of the Pfizer vaccine? Or is there something about this vaccine that means you must have the 2nd dose in 3 weeks or protection gone after short period? https://twitter.com/alexdfox/status/1336332746415775744 …
      1 reply 0 retweets 1 like
    6. Armchair epidemiologist (self-certified)‏ @yellingatwind 10 Dec 2020
      Replying to @yellingatwind @zeynep and

      I actually believe it is UNETHICAL to not consider strongly using whatever you have to vaccinate as many vulnerable people in hotspots as fast as possible.

      1 reply 1 retweet 1 like
    7. Stephen Goldstein‏ @stgoldst 10 Dec 2020
      Replying to @yellingatwind @zeynep and

      Oh, so now vaccinating per the successful clinical trial protocol is (all caps) unethical? That's a pretty staggering charge to level at people who are doing their best to follow the evidence.

      2 replies 0 retweets 3 likes
    8. Stephen Goldstein‏ @stgoldst 10 Dec 2020
      Replying to @stgoldst @yellingatwind and

      Ultimately, do we need input from scientists at all really?

      2 replies 0 retweets 1 like
    9. Armchair epidemiologist (self-certified)‏ @yellingatwind 10 Dec 2020
      Replying to @stgoldst @zeynep and

      Of course - this analysis needs input from immunologists, public health officials, epidemiologists, manufacturing experts, ethicists AND understanding of existing biases.

      1 reply 0 retweets 0 likes
    10. Stephen Goldstein‏ @stgoldst 10 Dec 2020
      Replying to @yellingatwind @zeynep and

      You just said definitively it’s unethical to not consider it. So if immunologists are saying it’s unequivocally a bad idea, they are unethical. Why seek the input of unethical people?

      2 replies 0 retweets 1 like
      zeynep tufekci‏Verified account @zeynep 10 Dec 2020
      Replying to @stgoldst @yellingatwind and

      We're not asking immunologists if it is a good or bad idea. That's not an immunology question. (How could it be?) We're asking for a discussion of the trade-off curve so people can decide if it is a good or bad idea. Besides, fractional dosing for shortage is done (YF etc.)

      8:50 AM - 10 Dec 2020
      • 1 Like
      • Armchair epidemiologist (self-certified)
      1 reply 0 retweets 1 like
        1. Armchair epidemiologist (self-certified)‏ @yellingatwind 10 Dec 2020
          Replying to @zeynep @stgoldst and

          What is YF? This definitely seems like a case of shortage where fractional dosing could be considered. Fractional being defined as one shot instead of two -> or 2/3 shot or whatever.

          0 replies 0 retweets 0 likes
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