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zeynep's profile
zeynep tufekci
zeynep tufekci
zeynep tufekci
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@zeynep

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zeynep tufekciVerified account

@zeynep

Complex systems, wicked problems. Society, technology, science and more. @UNC professor. @NYTimes columnist. My newsletter is @insight: http://www.theinsight.org 

floating in a most peculiar way
theinsight.org
Joined August 2009

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    1. Natalie E. Dean, PhD‏Verified account @nataliexdean 25 Nov 2020

      With respect to the AstraZeneca vaccine, I am guessing people think my objection is to science by press release, and that I want a peer-reviewed publication. But no, not really. What I want is reliable and definitive evidence to inform policies impacting millions. 1/4

      17 replies 122 retweets 834 likes
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    2. Natalie E. Dean, PhD‏Verified account @nataliexdean 25 Nov 2020

      If the answer is that AstraZeneca needs to go back and add a new half-dose arm to their trials so that they can prospectively evaluate its efficacy in diverse subgroups, then we have to carefully consider the value of a peer-reviewed publication at this moment. 2/4

      3 replies 19 retweets 246 likes
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    3. Natalie E. Dean, PhD‏Verified account @nataliexdean 25 Nov 2020

      We’ve written about this in @NEJM. Basically, there are risks to publishing results that are “promising but inconclusive.” Though it seems slower at the time, in the long run it is better to generate the conclusive evidence while we still can. 3/4https://www.nejm.org/doi/full/10.1056/NEJMsb1905390 …

      2 replies 38 retweets 283 likes
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    4. Natalie E. Dean, PhD‏Verified account @nataliexdean 25 Nov 2020

      I am very encouraged by the prospect of multiple safe and effective vaccines, particularly cheaper and easier to store vaccines, but these results have major policy implications. And implications for the public’s trust! We have to make sure we get it right. 4/4

      12 replies 25 retweets 341 likes
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      zeynep tufekci‏Verified account @zeynep 25 Nov 2020
      Replying to @nataliexdean

      Yeah the problem here isn’t science by press release. It’s a misleading, confusing press release—and that’s the best case scenario—and non-transparent and uninterpretable results. Given the stakes, this is inexcusable. They should step up very soon and provide answers.

      10:46 AM - 25 Nov 2020
      • 1 Retweet
      • 27 Likes
      • Beat SARS-CoV2-gether jonflip zooza aka whatsapp ricky Carly Connie AscanioAncona Jeff DeCoursey NK Leb Lorenso Asskoul
      2 replies 1 retweet 27 likes
        1. zeynep tufekci‏Verified account @zeynep 25 Nov 2020
          Replying to @zeynep @nataliexdean

          There was a dosing error, and here’s what we’re doing going ahead. Fine. Not this confusion. Not now.

          0 replies 0 retweets 14 likes
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        2. Jessica Pickett‏ @pickettjessica 25 Nov 2020
          Replying to @zeynep @nataliexdean

          Honestly, I think that this stems from partnering with a relatively inexperienced vaccine manufacturer. (Although technically Moderna has even less, they have also much more actively recruited from established competitors.)

          1 reply 0 retweets 1 like
        3. Jessica Pickett‏ @pickettjessica 25 Nov 2020
          Replying to @pickettjessica @zeynep @nataliexdean

          At least among innovator companies familiar with the regulatory approval process for entirely new products, that is. And while I like AstraZeneca’s strategy of licensing partnerships to improve global access, the tech transfer demands must have also stretched their team thin.

          1 reply 0 retweets 1 like
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