An underappreciated point here is that because the two regimens were apparently not randomized as part of the trial design, this trial wouldn't (according to normal standards) actually show that one is better than the other, even with sufficient statistical power. 1/2https://twitter.com/michaelmina_lab/status/1331027737780363273 …
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In particular, substantial differences in effectiveness could be due to population differences. This does not seem implausible, particularly for Adenovirus-based vaccines. 2/2
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Replying to @WesPegden
I think they're gonna have to do this one again.
7:18 AM - 24 Nov 2020
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