One day, we’ll figure out what made people look the other way when it comes to Vitamin D (too-good/-simple to be true? “Pauli effect”?). Til then, it’s not at all unlikely that thousands will have suffered needlessly ... and you can’t imagine how sad @zeynep’s reaction makes me.https://twitter.com/ljupc0/status/1327625284594638850 …
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What do you make of the French study that showed an effect of supplementation (I believe the sample was about 100 elderly patients)
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“Minimal supplementation” won’t cut it in the acute phase. The usual supplement form (cholecalciferol) is often given in baby doses _and_ takes a long while (~1 week, ask
@__ice9) to be metabolized. The Córdoba team used calcifediol for a good reason. -
Interestingly, we see that using massive doses of cholecalciferol does seem to help. My guess: it's probably partly compensating for the conversion delay to calcifediol. https://twitter.com/gshotwell/status/1327314544344043523?s=19 …
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A relatively recent, and good post on what we know about Vitamin D and Covid-19: https://coronavirus.medium.com/vitamin-d-and-covid-19-90f1d1493cc0 … (making a similar deficiency vs. supplemental point)
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I respect both of you. As a nurse, I know we undertest for Serum 25OH. Most clients are in low to deficient ranges. Some <10 ng/ml w/most in low 20s. Widespread deficiency prevalent esp. in Northern climates. So cheap/easy to supplement 2-4k iu D3/day. Decrease severity of Covid.
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Just for the record, I respect
@zeynep enormously.
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Worth educating about scale: I’m finally reading Gleick’s misnamed “Chaos” after 30 years, and it’s much more about scale (not to mention sociology of science).
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