Its totally fine to recommend masks & to note strengths & limits w data
But let's not go overboard and claim a cluster RCT was impossible. It certainly was possible in March. @mgtmccartney
Here is what is wrong with this op-ed: [thread]https://www.nytimes.com/2020/11/06/opinion/sunday/coronavirus-masks.html?smid=tw-share …
Claim that I don’t think we can do a randomized study on because it’s my “pet intervention” is exactly wrong. People want to do randomization because it’s their pet method, but the nature of the question doesn’t allow it. For PPE, yes. Source-control? Show me a feasible design.
-
-
For the record I’m not convinced it was or is worth doing this trial, but this is the design:https://www.nejm.org/doi/full/10.1056/NEJMoa1814556 …
-
I'll take a look. There are some ringworm studies that try to get at (some) benefit to others aspect as well, but in each instance I've seen, the intervention isn't as simple as a t-shirt someone can wrap around their face, thus you can try to randomize between communities.
- Show replies
New conversation -
-
-
Hospital data? Yes but that’s confounded by PPE effects. The thing we really want to get at, for which we have much less clinical data, is source control. That said, as I wrote, when you have a well-established mechanism and lab studies, those are just as evidence.
-
Im not sure what you mean by PPE effects — PPE (aside from masks) used only for care of known COVID patients, who are usually minimally infectious by that point, 7+ days into illness. Hospital transmission was mostly occurring from pre/asymptomatically infected staff and patients
- Show replies
New conversation -
Loading seems to be taking a while.
Twitter may be over capacity or experiencing a momentary hiccup. Try again or visit Twitter Status for more information.