Reason that past clinical studies, focusing on health-care worker outcomes, are not the best indicator is that masks for *source-control* is not an individual level variable. It's like asking if filters on car exhausts lower air pollution by measuring the air ... inside each car.
Dunno, "different genome" didn't seem to be of any protection in Wuhan. But look at Japan, then. Doesn't test widely, doesn't shut down, denial till late, does a few smart things for sure but very dense, subway heavily used. But, almost all masked. Control case.
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If that were as protective, what happened in Wuhan? I suspect previous exposure will play a big role, eventually, in putting the puzzle together (recent papers on T-cell cross-reactivity are strong signals) but it's obviously not enough because .. Wuhan.
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