Lockdown can't persist until a validated treatment or vaccine. I take COVID very seriously, and I don't think it's reasonable to pursue herd immunity. But we need to start seeing some solid proposals for the next phase of the war.
I'm not confident enough to be against it, but I'd look at it more like military service than a no-brainer. Permanent damage to the lungs and/or heart are real possibilities. You'd very plausibly be trading end-of-life years for cash or civic duty.
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If data shows that variolation reduces chance of hospitalization 3-30x (an enormous yet plausible effect size), then anyone who is currently risking getting a large dose from their environment (housemates, grocery runs, etc) can expect it's best to fold their cards and variolate
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I'm anxiously waiting to hear that someone is doing a variolation study together with all these vaccine challenge trials
End of conversation
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