If we're to trust the Wuhan data, it took 2 weeks for daily new cases to begin dropping. The good news is that once that begin, the decline was ~as steep as the growth. The bad news is that cumulative active cases continued to rise for some time.https://twitter.com/NateSilver538/status/1240689047418236932 …
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If you make it to the point where you see a decline in daily new cases *without* overwhelming your medical system, it's time to start reducing the most burdensome restrictions. If not, you probably want to wait for that fire to be put out.
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It's not clear that you want to reduce the restrictions even at that point. If you want to assume that herd immunity is not a thing, you can't relax lock down until the entire US population has stopped seeing new cases.
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The infamous Biogen meeting in the Boston area was Feb 26-27; the big bump in MA numbers was March 10. So, yes, there's your two weeks.
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