The Guinea worm infects humans via contaminated drinking water, migrating through the tissues & causing severe pain before emerging through the legs or feet
In 1986, there were ~3.5 million cases
In 2017, there were *thirty* reported cases. 3-0.
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Wow. I actually remember it being a huge problem - had no idea things had improved that much.
“Guinea worm disease is set to become the second human disease in history, after smallpox, to be eradicated. It will be the first parasitic disease to be eradicated and the first disease to be eradicated without the use of a vaccine or medicine.” 
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Good riddance.
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