Vince Buffalo

@vsbuffalo

Postdoc in evolutionary genetics. ♥s biology, probability, statistics, climbing, fly fishing, backpacking. Author of the book Bioinformatics Data Skills.

Eugene, OR
Joined August 2009

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  1. Pinned Tweet
    9 Oct 2019

    My latest with , where we use the ideas from our previous paper to reanalyze three evolve and resequence studies. We find a strong genome-wide effect of linked selection across short timescales, a reversal in the direction of selection, and more!

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  2. 15 hours ago

    Listening to Marisa Anderson while coding up some bootstrap CIs for a non-linear least squares model I've estimated. It appears this is another good example of why non pivot-based CIs are dangerous and misleading.

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  3. Retweeted
    Feb 2

    One of the nice things about Andrew Gelman's blog is how benign posts routinely produce deep debates about foundations of statistics. This time, the concept of "calibration" (see comments): My attitude (new box in 2nd ed of my book):

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  4. Retweeted
    20 hours ago

    This was Stephen J. Gould’s favorite example of an “organ of extreme perfection” sensu Darwin, that evolved through gradual steps...it is *of course* driven by a parasitic life history. I urge you to watch this. It’s one of the most amazing adaptations...

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  5. Retweeted
    20 hours ago

    “What did genes do to deserve their sinister, juggernaut-like reputation? ... Why are genes thought to be so much more fixed and inescapable in their effects than television, nuns, or books?” (Dawkins, The Extended Phenotype)

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  6. Retweeted
    Feb 1

    In the past week people have correctly expressed concern over the twitter piling-on re . I want to share a few thoughts about whether twitter is a suitable place for this to play out... [thread]

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  7. Jan 31

    WTF happened to skepticism in the sciences? Why does this have so many RTs and likes? Why do scientists participate in spreading hysteria before we know all the facts?

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  8. Retweeted
    Jan 31

    These short inserts do indeed exist in relative to its closest sequenced relative (BetaCoV/bat/Yunnan/RaTG13/2013, seen here ). However, a simple BLAST of such short sequences shows match to a huge variety of organisms. No reason to conclude HIV.

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  9. Retweeted
    Jan 31

    There are many raw data files to sort through, and this is an added burden to a group of stressed co-authors. If anyone here is willing to volunteer a few hours to delve into data files to confirm there are no sources of concern (hopefully), or identify concerns, please reply

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  10. Retweeted
    Jan 30

    An updated version of our ( and ) work on the factors affecting the performance of polygenic scores--beyond genetic ancestry—is accepted and now up [thread]

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  11. Jan 30

    Scientists should not feel anxious about open data or open code — I think the cultural norms that can lead to this sort of anxiety need to change:

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  12. Retweeted
    Jan 30

    This. We should not rush to judgement on any one paper. The AmNat retraction took 2 months from first hearing concerns to the official announcement because we wanted to be methodical in evaluating the issue.

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  13. Retweeted
    Jan 30

    "object of type 'closure' is not subsettable" 👆 is a talk I gave at on getting unstuck and debugging in Slides and other resources are here:

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  14. Jan 30

    The Kern-Ralph colab got a Correlated History of Earth! Best poster ever — I have one at home.

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  15. Retweeted
    Jan 30

    A comment on blog: we ( and others) started our investigations after being alerted by a junior scientist with inside information. I am most grateful to this . This anonymous scientist deserves our thanks and gratitude

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  16. Jan 30

    Second key on the newish 13" Macbook Pro has died. These keyboards are bloody awful. But even worse: the new 13" MacBook Pros have the touchpad without an escape key.

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  17. Retweeted
    Jan 30

    Now up on Eco-Evo Evo-Eco blog, two posts on The first is a neutral narrative about my role and insight. The second link to a growing spreadsheet listing retractions, questions, and papers that are confirmed to be OK

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  18. Jan 30

    Honestly, if the field doesn't make large systematic changes that actually alter incentive structures, we haven't learned our lesson. How hard is it to create a shadow journal of well-conducted experiments that find negative results?

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  19. Jan 30

    Why do journals need to publish negative results? This is why 👇

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  20. Retweeted
    Jan 30

    *Signal boost* This is obviously horrible for the co-authors. It is equally horrible for all the missing bullet wounds on the airplane. We'll never know how many students didn't get to publish their work, or spent time trying to replicate something that was fabricated 1/N

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  21. Retweeted
    Jan 30

    Stats folks - do you teach how to identify and present negative results? How about messy results?

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