I don't actually get how gene therapy is supposed to work. Do the crispr type edits affect ongoing expression in mature cells? Could you actually change skin/eye/hair color like that n. korean badguy in that james bond movie?
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Replying to @vgr
Too complex for tweets. Various ways of getting new genes in / editing existing genes in cells, delivering payload to target cells, different effects/tradeoffs. I'm working on designing gene therapy cure for diabetes. Will provide reference to review article(s) later.
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