What if climate change breaks civilization?
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what if the multiple universe theory is correct and we learn to travel between such universes? What would change? What would we value?
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what if each individual created his/her own reality as they go along
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Or, just some of them
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none of us lives to 200 until all of us live to 200

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What if we could live to each be 200 or more? ;-)
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what if electricity was all clean, renewable and approaching nominal cost
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a deeply-felt feeling of realization that humans are really weird in comparison to other biological species.
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gene editing - I have many ideas about how it affects society that are totally not crackpot at all
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ooh star-bellied sneetch time
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