I went to school in not-Boston. I did my few years of tech work in not-Silicon Valley. I've done/do all my writing in not-New-York.
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Conjecture: If originality and independence are your primary considerations, not-there is probably the best place to do your work.
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In generally the cost of originality and independence is that you must sacrifice almost every possible source of leverage
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But if you can identify a clear source of leverage that would make a huge difference to your preferred form of creative work, just go there
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