It's funny how people think a post-apocalyptic landscape will be relatively flat socioeconomically. At most they think there will be small-scale warlords or Dunbar-scale anarchist communes. No. There will be deathstar billionaires with private armies and narrow-deep tech stacks.
Lots of refactoring needed, but economies of scale are about learning rather than scale. Once the learning is complete, you can actually scale down. A lot more steel is now made in mini-steel plants (electric arc furnaces) than integrated large scale ones for example.
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In general you're right that process industries tend to get bigger and bigger, more and more centralized, but after the learning is done, that's typically because of a volume profitability model, not fundamental efficiency
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