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unless you have math, or are really into layouts, let the publisher do the hard work. the layout is no longer static. also, latex and equations fail badly in all e book formats.
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My first 3 ebooks were latex --> html --> epub and worked quite well, but it is admittedly a janky process to get it to work. My only p-book was latex, despite not having any math. I've self-published all my stuff so far, you're not talking to J. K. Rowling here :D
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Adjacently, InDesign supports auto-populating data from external sources, so one can have a template and generate content from YAML or some other format
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Alas, I don’t think there is software that would completely handle all specific aspects of book production, especially related to typesetting, better than InDesign. CSS is far from there still…