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Prikvačeni tweet
Our work reporting 523 new samples, the largest ancient DNA study to date, and the most widely accessed genomics preprint on bioRxiv, detailing the parallel genomic history of Europe and South Asia over the past 10000 years, is now out in
@sciencemagazine. https://scholar.harvard.edu/vagheesh/centralsouthasia …pic.twitter.com/m3mKdrebz4
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Vagheesh Narasimhan proslijedio/la je Tweet
One of the perks of this course: listening to Shamil tracing the history of infinitesimal model to 1887! https://twitter.com/arbywho/status/1222995756484788225 …pic.twitter.com/rs6d50nufz
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Vagheesh Narasimhan proslijedio/la je TweetHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi
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Vagheesh Narasimhan proslijedio/la je Tweet
Really nice volume with chapters by leaders in statistical population genetics. Open access material.https://twitter.com/jeromekelleher/status/1220662412464087042 …
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Vagheesh Narasimhan proslijedio/la je Tweet
Excited to share our preprint on estimating regional polygenicty for complex traits from GWAS. And shoutout to former BIG summer (
@UCLAQCBio ) undergrad Mario for his great contribution to the paper.@ksburch_@kangchenghou@bpasaniuc@sr_sankararamanhttps://www.biorxiv.org/content/10.1101/2020.01.15.908095v1 …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Vagheesh Narasimhan proslijedio/la je Tweet
Study estimates that just differences in linkage disequilibrium & allele frequency explain ~70% of relative accuracy loss when using European-derived polygenic scores in individuals of African ancestry https://www.biorxiv.org/content/10.1101/2020.01.14.905927v1 …
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Vagheesh Narasimhan proslijedio/la je Tweet
Consider: millions of years ago our antecedents gave a massive sacrifice of their left hemisphere. We lost a tremendous amount of short term memory and replaced it with Broca’s, Wernicke & the phonological loop. But why? So we can—talk. Thus chimpanzees can do this—we can’t:pic.twitter.com/CDznxg37p1
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Vagheesh Narasimhan proslijedio/la je Tweet
In a comparison of 18 dimension reduction/matrix factorization methods on 30 publicly available Single Cell RNAseq data sets, the simplest and oldest methods do surprisingly well compared to the new kids on the block. Nice work from Zhou lab
@bioconductor https://www.biorxiv.org/content/10.1101/641142v2 …pic.twitter.com/SUzD9pvWCb
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Vagheesh Narasimhan proslijedio/la je Tweet
Early x-mas present! Our paper on HOPS, the first metagenomic alignment tool dedicated to ancient DNA, has been published. https://genomebiology.biomedcentral.com/articles/10.1186/s13059-019-1903-0 …pic.twitter.com/sizkSMdI42
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Vagheesh Narasimhan proslijedio/la je Tweet
Extremely excited to share the first major project from our lab, led by the brilliant
@dpowell_daniel with major contributions from Mateo Garcia, Mackenzie Keegan,@lepatoptera,@pandolfatto,@gilrosenthal, Manfred Schartl, and other co-authors:https://biorxiv.org/cgi/content/short/2019.12.12.874586v1 …Prikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Vagheesh Narasimhan proslijedio/la je Tweet
Remarkable team effort with 100s of collaborators: cross-disorder genetics across 8 psych disorders (N = 727K)
@PGCgenetics Analyses led by Phil Lee, w/@AnttilaVerneri@hyejung_won@AnnejaneF@Andrew_Grotz@tuckerdrob@michelnivard Ken Kendler + many more https://authors.elsevier.com/a/1aDRcL7PXYX9u#.XfJwJzLalm8.twitter …pic.twitter.com/e5e8nHbSYR
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Vagheesh Narasimhan proslijedio/la je Tweet
Pretty crazy
@biorxivpreprint from@pastramimachine: neural nets can predict the *geographical origin* of actual human samples (from HGDP) with a median prediction error of 85km
.... and the largest errors are explainable by known patterns of migration https://www.biorxiv.org/content/10.1101/2019.12.11.872051v1 …pic.twitter.com/KGIP3N36jS
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Vagheesh Narasimhan proslijedio/la je Tweet
(Thread) New preprint out. Population genetics of the coral Acropora millepora: Towards a genomic predictor of bleaching. https://www.biorxiv.org/content/10.1101/867754v1 … We are very excited about this work, here a few of the highlights (1/n)
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Heard Andrew Peterson present a teaser of this at ASHG - great to see this out. https://www.nature.com/articles/s41586-019-1793-z#Sec6 …
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Vagheesh Narasimhan proslijedio/la je Tweet
Excited to present our work on PRS and lifespan with
@masakanai@dalygene@okada_yukinori. To translate genetics into improving human health beyond mapping of GWAS variants, we explored PRS associations with lifespan in 676K people of BioBank Japan,@uk_biobank and@FinnGen_FI.
https://twitter.com/biorxiv_genetic/status/1200645219408130052 …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Vagheesh Narasimhan proslijedio/la je Tweet
fastGWA is ~89 times faster and only requires ~5% of RAM compared to BOLT-LMM-Inf in a data set with n=456,422 and m=8,531,416, and even ~4 times faster than PLINK2. fastGWA summary statistics for >2000 traits from the UK Biobank are available at http://fastgwa.info .https://twitter.com/NatureGenet/status/1199013689405399040 …
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Vagheesh Narasimhan proslijedio/la je Tweet
Whoa! A major breakthrough in sorghum, gene editing has elevated the protein of this important crop from 9-10% to a staggering 15-16%. Also improved digestibility. A big deal for Africa & India, another reason to embrace NBT, remove regulatory hurdleshttps://www.queenslandcountrylife.com.au/story/6500841/gene-editing-delivers-major-sorghum-protein-lift/ …
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Vagheesh Narasimhan proslijedio/la je Tweet
Really excited to see our work on mosaic Y chromosome loss out today in
@nature. Many thanks to all involved, and especially to all the@uk_biobank and@23andMe research participants who made this possible. https://www.nature.com/articles/s41586-019-1765-3 …Prikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Vagheesh Narasimhan proslijedio/la je Tweet
Amazing! “After the CRISPR therapy, Gray’s total hemoglobin reached normal levels; of which 47% was fetal hemoglobin. It’s thought that a fetal hemoglobin level of 25%-30% is sufficient to “cure” a patient with sickle cell disease.“ New era of single, transformative therapieshttps://twitter.com/adamfeuerstein/status/1196760642969112578 …
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Vagheesh Narasimhan proslijedio/la je Tweet
Puzzling results in comparing mutation rates in humans and baboons. Great collaboration with Felix Wu,
@molly_przew, Alva Strand, Jeff Wall and Carole Ober.https://www.biorxiv.org/content/10.1101/844910v1 …Prikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Vagheesh Narasimhan proslijedio/la je Tweet
Remember legendary naturalist Alfred Russel Wallace
#OnThisDay. Wallace co-discovered evolution through natural selection during an 8-year journey through Southeast Asia, a trek that spanned over 14,000 miles and resulted in the collection of over 125,000 specimens.pic.twitter.com/lPgMJGawin
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