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ultimape's profile
UltimApe 🐜💩💛
UltimApe 🐜💩💛
UltimApe  🐜 💩 💛
@ultimape

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UltimApe  🐜 💩 💛

@ultimape

Aspiring cyborg & informavore. Weaver of existential dread. Stories masked in a cocoon of insight porn and body horror. Wandering scholar.

The Spider's Web.
keybase.io/ultimape
Joined September 2008

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    1. UltimApe  🐜 💩 💛‏ @ultimape 13 Dec 2017
      Replying to @ultimape

      Turns out the common vitamin form of Niacin in my Multivitamin (inositol niacinate) doesn't cause a flush response either regardless of etiology... and this means it is probably not any good as a Niacin vitamin supplement. Guess I'll have to get a more specific kind.

      1 reply 0 retweets 0 likes
    2. UltimApe  🐜 💩 💛‏ @ultimape 14 Dec 2017
      Replying to @ultimape

      A Hunch on skin and cholesterol issues lead me to some weird ideas. http://www.bbc.com/news/health-31585299 … http://www.manchester.ac.uk/discover/news/skin-odour-could-lead-to-early-diagnosis-of-parkinsons/ … https://www.ncbi.nlm.nih.gov/pubmed/23775688  https://www.ncbi.nlm.nih.gov/pubmed/26297828  https://www.nature.com/articles/srep12081 …https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098634/ …

      1 reply 0 retweets 0 likes
    3. UltimApe  🐜 💩 💛‏ @ultimape 14 Dec 2017
      Replying to @ultimape

      and Alpha-synuclein is an immune system issue in parkinsons https://www.ncbi.nlm.nih.gov/pubmed/25588354  oh and yeah... those two chemicals in the skin seem to have unique ratios in autism. https://www.ncbi.nlm.nih.gov/pubmed/26479762 

      1 reply 0 retweets 0 likes
    4. UltimApe  🐜 💩 💛‏ @ultimape 14 Dec 2017
      Replying to @ultimape

      Seems like lion's mane may have action on the same areas and shows promise in mouse models. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4797317/ … and they used the method described here (a study on that alpha-synuclein protein): https://www.ncbi.nlm.nih.gov/pubmed/21193046  to test motor improvements

      1 reply 0 retweets 0 likes
    5. UltimApe  🐜 💩 💛‏ @ultimape 17 Dec 2017
      Replying to @ultimape

      UltimApe  🐜 💩 💛 Retweeted UltimApe  🐜 💩 💛

      Thinking about it more deeply, this idea isn't just a hunch. I know for a fact that there's misinformation that has later been shown not to be 'purely' genetic, but microbiome based.https://twitter.com/ultimape/status/941645164145270785 …

      UltimApe  🐜 💩 💛 added,

      UltimApe  🐜 💩 💛 @ultimape
      Replying to @ultimape @AmandaChimera
      Hunch: Microbiomes seems to be a novel thing in science literature. Paradigm assumes genes are only heritable thing... But we also pass on our microbiome. If they're framing the problem wrong it explains why there is low level noise about epigenetics many scientists discount.
      1 reply 0 retweets 0 likes
    6. UltimApe  🐜 💩 💛‏ @ultimape 17 Dec 2017
      Replying to @ultimape

      UltimApe  🐜 💩 💛 Retweeted UltimApe  🐜 💩 💛

      I can't find the article, but there was even a pretty big back & forth between Dawkins and E.O. Wilson on the origin of cultural evolution that ended oddly (IMHO in a draw)https://twitter.com/ultimape/status/861365458666180608 …

      UltimApe  🐜 💩 💛 added,

      UltimApe  🐜 💩 💛 @ultimape
      Replying to @ultimape
      Hofstadter Pinker Dennet Wilson and Dawkins are all arguing over who's map is correct. They're locked into a system of prestige.
      1 reply 0 retweets 1 like
    7. UltimApe  🐜 💩 💛‏ @ultimape 17 Dec 2017
      Replying to @ultimape

      A lot of old evidence, like this snippet (from a 1983 article in the NYTIMES) discusses, has actually been shown to be mediated by our microbiome to some extent. http://www.nytimes.com/1983/04/24/books/is-our-culture-in-our-genes.html?pagewanted=all …pic.twitter.com/DGxoY403uH

      1 reply 0 retweets 0 likes
    8. UltimApe  🐜 💩 💛‏ @ultimape 17 Dec 2017
      Replying to @ultimape

      It isn't JUST our genes being passed on that affect our tendency to choose food... But this goes against established dogma. https://www.sciencedirect.com/science/article/pii/S0960982213004181 … https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270213/ … https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3957428/ … https://chriskresser.com/do-gut-microbes-control-your-food-cravings/ …https://www.scientificamerican.com/article/how-gut-bacteria-tell-their-hosts-what-to-eat/ …

      1 reply 1 retweet 3 likes
    9. UltimApe  🐜 💩 💛‏ @ultimape 17 Dec 2017
      Replying to @ultimape

      And... It isn't just humans. https://ccb.ucr.edu/shipleyfiles/2016_proposal_hale_amanda_shipley-skinner_proposal.pdf …pic.twitter.com/T741BkDAov

      1 reply 0 retweets 0 likes
    10. UltimApe  🐜 💩 💛‏ @ultimape 17 Dec 2017
      Replying to @ultimape

      And this shit is way more complicated than just some simple Mendelian genetic inheritance model. " it's not just what the Hadza eat that contribute to their remarkable gut flora, it's where and how they are eating it, too." https://www.wired.com/2014/04/hadza-hunter-gatherer-gut-microbiome/ …pic.twitter.com/6J8vrhhZbH

      2 replies 0 retweets 0 likes
      UltimApe  🐜 💩 💛‏ @ultimape 23 Jun 2018

      I'm hearing disturbing rumors that Alzheimer's might be associated with a viral contagion of some kind, perhaps one that affects insulin regulation thru immune suppression action on the serotonin systems in our body. Funny that.

      10:01 PM - 23 Jun 2018
      1 reply 0 retweets 0 likes
        1. New conversation
        2. UltimApe  🐜 💩 💛‏ @ultimape 23 Jun 2018
          Replying to @ultimape

          Women with PCOS have a higher risk for Alzheimer's disease, and yet Autism in males seems to be protective of memory degradation you say? Would be a weird coincidence if estrogen had a big impact on serotonin regulation. Oh wait.

          1 reply 0 retweets 0 likes
        3. UltimApe  🐜 💩 💛‏ @ultimape 23 Jun 2018
          Replying to @ultimape

          Damn shame we don't have entire classes of viruses who operate by subverting the immune system's response in a way that creates persistent dysfunction in the microbiome's ability to produce serotonin long after the infection has gone away. You know, stuff that affects beta cells.

          1 reply 0 retweets 0 likes
        4. UltimApe  🐜 💩 💛‏ @ultimape 23 Jun 2018
          Replying to @ultimape

          Odd how fasting seems to help with autism symptoms, PCOS symptoms, improvement in Alzheimer's and MS and Parkinsons'. Its almost like they might all stem from some kind of immune response. One perhaps leading to a microbiome imbalance causing sweet-tooth craving via the amygdala.

          1 reply 0 retweets 0 likes
        5. UltimApe  🐜 💩 💛‏ @ultimape 23 Jun 2018
          Replying to @ultimape

          It'd be really weird if stuff like spearmint and rosemary were somehow protective against Alzheimers while also having an impact on PCOS, Type II diabetes, and Autism symptoms. You'd think that it might be an effect on the microbiome's ability to regulate associated hormones.

          1 reply 0 retweets 0 likes
        6. UltimApe  🐜 💩 💛‏ @ultimape 23 Jun 2018
          Replying to @ultimape

          What is sundowning, and why would that have anything to do with serotonin balance issues associated with the body's circadian rhythm? What even is the mitochondria roll in adipose tissue? Why does my body temperature seem to be markedly lower when I experience demented states?

          1 reply 0 retweets 0 likes
        7. UltimApe  🐜 💩 💛‏ @ultimape 23 Jun 2018
          Replying to @ultimape

          UltimApe  🐜 💩 💛 Retweeted UltimApe  🐜 💩 💛

          Hunches, Long hunches grown from nagging questions. Einstien's obsession with compasses.https://mobile.twitter.com/ultimape/status/823454755850752000 …

          UltimApe  🐜 💩 💛 added,

          UltimApe  🐜 💩 💛 @ultimape
          Bees clump to maintain homeostasis. Bees kill wasp invaders to the "body" by boiling them. Tell me, why do we fever? #beehiveiorism pic.twitter.com/SJU3hwWj8f
          1 reply 0 retweets 0 likes
        8. UltimApe  🐜 💩 💛‏ @ultimape 23 Jun 2018
          Replying to @ultimape

          UltimApe  🐜 💩 💛 Retweeted UltimApe  🐜 💩 💛

          An autistic self obsession. What am I?https://mobile.twitter.com/ultimape/status/816520733878812672 …

          UltimApe  🐜 💩 💛 added,

          UltimApe  🐜 💩 💛 @ultimape
          Why am I different?
          1 reply 0 retweets 0 likes
        9. UltimApe  🐜 💩 💛‏ @ultimape 23 Jun 2018
          Replying to @ultimape

          UltimApe  🐜 💩 💛 Retweeted UltimApe  🐜 💩 💛

          Why do we fever?https://mobile.twitter.com/ultimape/status/931515851827793921 …

          UltimApe  🐜 💩 💛 added,

          UltimApe  🐜 💩 💛 @ultimape
          Replying to @ultimape
          What are we missing? Why are we burning? https://twitter.com/ultimape/status/928170697893007362 …
          1 reply 0 retweets 0 likes
        10. UltimApe  🐜 💩 💛‏ @ultimape 23 Jun 2018
          Replying to @ultimape

          Parasites. Dementors. Literally figurative bacterial demons who prey on your fears? Your fear centers.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185127/ …

          1 reply 0 retweets 2 likes
        11. UltimApe  🐜 💩 💛‏ @ultimape 23 Jun 2018
          Replying to @ultimape

          Why does choline seem to improve brain function while also being shown to reduce alzhimer's risk? What does lipid processing system and cholesterol have to do with brain function? How the liver produces estrogen? What does serotonin regulate in the body? What is the vagal nerve?

          1 reply 0 retweets 2 likes
        12. UltimApe  🐜 💩 💛‏ @ultimape 23 Jun 2018
          Replying to @ultimape

          Doctor said she's never seen someone do a 3 day fast and not regain their weight back. Doctor doesn't understand insulin regulation. The fast was just a shortcut to fix my gut demons. I fixed my anhedonia, doctors still don't care.

          1 reply 0 retweets 2 likes
        13. UltimApe  🐜 💩 💛‏ @ultimape 23 Jun 2018
          Replying to @ultimape

          Why is the life expectancy of an autistic person ~36 years old?

          1 reply 0 retweets 1 like
        14. UltimApe  🐜 💩 💛‏ @ultimape 23 Jun 2018
          Replying to @ultimape

          “Autistic people and their families need reassurance from government and the NHS that this is going to be taken seriously and action will be taken.”https://www.theguardian.com/science/2016/mar/18/premature-autism-deaths-are-hidden-crisis-says-charity …

          1 reply 0 retweets 1 like
        15. UltimApe  🐜 💩 💛‏ @ultimape 23 Jun 2018
          Replying to @ultimape

          UltimApe  🐜 💩 💛 Retweeted UltimApe  🐜 💩 💛

          Dear government, will you solve my autism problem? All these scared mommy's and daddy's seem to think you can cure my demons for me. Maybe you can innovate faster than I can?https://twitter.com/ultimape/status/799395625603309568 …

          UltimApe  🐜 💩 💛 added,

          UltimApe  🐜 💩 💛 @ultimape
          Replying to @ultimape
          "If you're deeply committed to innovation, you have to resist that there's only one innovation paradigm" — @zefrank http://www.inc.com/christine-lagorio/buzzfeed-2016-company-of-the-year-nominee.html … pic.twitter.com/oUaPiXS0fN
          1 reply 0 retweets 1 like
        16. UltimApe  🐜 💩 💛‏ @ultimape 23 Jun 2018
          Replying to @ultimape

          UltimApe  🐜 💩 💛 Retweeted

          Is this a joke? https://twitter.com/ultimape/status/923217124692234245 …

          UltimApe  🐜 💩 💛 added,

          This Tweet is unavailable.
          1 reply 0 retweets 0 likes
        17. UltimApe  🐜 💩 💛‏ @ultimape 23 Jun 2018
          Replying to @ultimape

          UltimApe  🐜 💩 💛 Retweeted UltimApe  🐜 💩 💛

          I don't know how old I am. I don't know what day it is. I don't know how much time I have left on this earth. I don't trust the united nanny state with my care.https://twitter.com/ultimape/status/918927483143061504 …

          UltimApe  🐜 💩 💛 added,

          UltimApe  🐜 💩 💛 @ultimape
          DIY healthcare is about changing the game we are playing with our lives. https://twitter.com/ultimape/status/800111545430736897 …
          Show this thread
          1 reply 0 retweets 1 like
        18. UltimApe  🐜 💩 💛‏ @ultimape 23 Jun 2018
          Replying to @ultimape

          UltimApe  🐜 💩 💛 Retweeted UltimApe  🐜 💩 💛

          I want to live forever. So far, so good. N=1https://twitter.com/ultimape/status/887412937845088257 …

          UltimApe  🐜 💩 💛 added,

          UltimApe  🐜 💩 💛 @ultimape
          Replying to @ultimape
          "N-of-1 trials can be a messy way of looking at things, but they provide important clues about what’s going on" https://spectrumnews.org/features/deep-dive/the-innovators-how-families-launch-their-own-autism-studies/ … pic.twitter.com/yjx3DRybNy
          1 reply 0 retweets 3 likes
        19. UltimApe  🐜 💩 💛‏ @ultimape 23 Jun 2018
          Replying to @ultimape

          UltimApe  🐜 💩 💛 Retweeted UltimApe  🐜 💩 💛

          While the larger political diaspora are bitching about the price of insulin and the cost of disease. I'm trying to fucking cure it. I am the walking dead.https://twitter.com/ultimape/status/866400309555470338 …

          UltimApe  🐜 💩 💛 added,

          UltimApe  🐜 💩 💛 @ultimape
          Convince me I'm not a P-Zombie.
          1 reply 0 retweets 4 likes
        20. UltimApe  🐜 💩 💛‏ @ultimape 23 Jun 2018
          Replying to @ultimape

          UltimApe  🐜 💩 💛 Retweeted UltimApe  🐜 💩 💛

          A zombie ant fighting off brain parasites and demonic gut bacteria. Monsters killing my friends off before we can find a way to be free from what plagues us. Living like Diogenes. A dog in his car. Less than human.https://twitter.com/ultimape/status/1004648436896010240 …

          UltimApe  🐜 💩 💛 added,

          UltimApe  🐜 💩 💛 @ultimape
          Fight your monsters. If you have energy to spare, fight other people's monsters. "The monster is my new name for my lifelong inability to do things on purpose." https://grognor.blogspot.com/2016/12/the-monster.html …
          Show this thread
          1 reply 0 retweets 0 likes
        21. UltimApe  🐜 💩 💛‏ @ultimape 23 Jun 2018
          Replying to @ultimape

          "There was no help available to her that did not begin with her having to magically overcome the same developmental disabilities that were hindering her from getting care." https://www.oregonlive.com/portland/index.ssf/2018/06/woman_who_set_self_on_fire_in.html … We are the walking dead.

          1 reply 0 retweets 0 likes
        22. UltimApe  🐜 💩 💛‏ @ultimape 23 Jun 2018
          Replying to @ultimape

          UltimApe  🐜 💩 💛 Retweeted

          I ask again. Is this a joke? Whatever it is, its sure seems to be playing out like a tragedy. https://twitter.com/ultimape/status/1010763971236855815 …

          UltimApe  🐜 💩 💛 added,

          This Tweet is unavailable.
          1 reply 0 retweets 0 likes
        23. UltimApe  🐜 💩 💛‏ @ultimape 23 Jun 2018
          Replying to @ultimape

          If this is meant to be a joke, I'm not laughing. I don't laugh at cruel irony. "The children of today being born with autism spectrum disorders will be the future adults of tomorrow. So what will happen to these individuals?"https://www.neoch.org/chronicle-203-articles/2013/10/22/high-functioning-autism-can-lead-to-the-streets.html …

          1 reply 0 retweets 0 likes
        24. UltimApe  🐜 💩 💛‏ @ultimape 23 Jun 2018
          Replying to @ultimape

          UltimApe  🐜 💩 💛 Retweeted UltimApe  🐜 💩 💛

          I literally don't laugh at cruel irony...https://twitter.com/ultimape/status/886775196908171264 …

          UltimApe  🐜 💩 💛 added,

          UltimApe  🐜 💩 💛 @ultimape
          Replying to @ultimape
          Schadenfreude is rooted in equality via envy or jealousy. Also, social science is basically systematized trolling. http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0100233 … pic.twitter.com/HQeGy0mNvV
          1 reply 0 retweets 0 likes
        25. UltimApe  🐜 💩 💛‏ @ultimape 23 Jun 2018
          Replying to @ultimape

          UltimApe  🐜 💩 💛 Retweeted UltimApe  🐜 💩 💛

          Jokes aside. Thank you for listening.https://mobile.twitter.com/ultimape/status/829112097955049472 …

          UltimApe  🐜 💩 💛 added,

          UltimApe  🐜 💩 💛 @ultimape
          Replying to @ultimape
          I know it helps knowing I'm not alone; That these challenges aren't unique. I figure others who aren't as brave might want to hear it too.
          1 reply 0 retweets 1 like
        26. UltimApe  🐜 💩 💛‏ @ultimape 8 Jul 2018
          Replying to @ultimape

          "immune system affects -- and even controls -- social behavior, a new study has found. [...] The discovery could have enormous implications for neurological conditions such as autism and schizophrenia." https://www.sciencedaily.com/releases/2016/07/160713143156.htm … My dog butt theory of autism strike again. Shocking.

          1 reply 0 retweets 0 likes
        27. UltimApe  🐜 💩 💛‏ @ultimape 8 Jul 2018
          Replying to @ultimape

          I am electrified with sarcasm that even I don't really understand.

          1 reply 0 retweets 0 likes
        28. UltimApe  🐜 💩 💛‏ @ultimape 8 Jul 2018
          Replying to @ultimape

          "shocked"

          1 reply 0 retweets 0 likes
        29. UltimApe  🐜 💩 💛‏ @ultimape 6 Sep 2018
          Replying to @ultimape

          "Ultimately, we think that using clear and temporally focused language can set us on a path to better deduce etiology and develop effective prevention and intervention efforts for health conditions that impact the lives of autistic individuals. " https://www.ncbi.nlm.nih.gov/pubmed/30184325 pic.twitter.com/GDxxd41FrW

          1 reply 0 retweets 0 likes
        30. UltimApe  🐜 💩 💛‏ @ultimape 1 Oct 2018
          Replying to @ultimape

          Science: We have no idea how all of this works. Me: I'm exploring the dietary habits of gay bears and how changes in food availability and environmental factors lead to large scale behavioral changes driven by a feedback loop between genes, brain and gut. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6141752/ …pic.twitter.com/p1dSB9UQlO

          1 reply 0 retweets 1 like
        31. UltimApe  🐜 💩 💛‏ @ultimape 22 Oct 2018
          Replying to @ultimape

          Modern microbiome trends in research amount to introducing bighorn sheep into yellow stone and wondering why they don't migrate. https://www.theatlantic.com/science/archive/2018/09/to-save-animals-we-need-to-save-their-knowledge-too/569503/ … and is about as fucked as our predictions on introducing wolves into the environment. https://www.nps.gov/yell/learn/nature/wolf-restoration.htm …pic.twitter.com/7AVf4GgQzm

          1 reply 0 retweets 0 likes
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