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trvrb's profile
Trevor Bedford
Trevor Bedford
Trevor Bedford
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@trvrb

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Trevor BedfordVerified account

@trvrb

Scientist @fredhutch, studying viruses, evolution and immunity. Collection of #COVID19 threads here: https://bedford.io/misc/twitter/ 

Seattle, WA
bedford.io
Joined December 2010

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    Trevor Bedford‏Verified account @trvrb 30 Apr 2020

    I know all the discussion is about a possible "2nd wave", but I've found this odd given that we haven't finished the first one. I would think quite possible that, nationally, we're in for a scenario of a long plateau. 1/10

    2:45 PM - 30 Apr 2020
    • 3,281 Retweets
    • 11,850 Likes
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    264 replies 3,281 retweets 11,850 likes
      1. New conversation
      2. Trevor Bedford‏Verified account @trvrb 30 Apr 2020

        If we look at confirmed cases through time in the US, we see a plateau of ~30k confirmed cases per day for basically the entire month of April. This corresponds to a decrease of the effective reproduction number to ~1. Figure from @cmmid_lshtm's https://epiforecasts.io/covid/ . 2/10pic.twitter.com/4SeiSAVGGU

        38 replies 285 retweets 1,256 likes
        Show this thread
      3. Trevor Bedford‏Verified account @trvrb 30 Apr 2020

        Trevor Bedford Retweeted Trevor Bedford

        As stated before, it's clear that social distancing has had a large impact on transmission (https://twitter.com/trvrb/status/1248096610887675904 …). However, this effect has been shy of suppression nationally and hence the plateau in cases rather than a consistent decrease. 3/10

        Trevor Bedford added,

        Trevor BedfordVerified account @trvrb
        In many ways, this should be entirely obvious, but we now have strong evidence that social distancing results in decreased #COVID19 transmission rates. 1/7
        Show this thread
        19 replies 311 retweets 1,490 likes
        Show this thread
      4. Trevor Bedford‏Verified account @trvrb 30 Apr 2020

        This plateau at a national level is the result of some states with rising case counts (and Rt greater than 1) and other states with falling case counts (and Rt less than 1). 4/10pic.twitter.com/Fd1iWA7Z3s

        9 replies 204 retweets 1,064 likes
        Show this thread
      5. Trevor Bedford‏Verified account @trvrb 30 Apr 2020

        As we move forward into summer, transmission rate will be affected by: 1. efforts to get society and the economy moving again 2. better knowledge and hygiene practices 3. possible impact of seasonality 5/10

        10 replies 154 retweets 1,098 likes
        Show this thread
      6. Trevor Bedford‏Verified account @trvrb 30 Apr 2020

        In terms of seasonality, there is increasing evidence of the importance to transmission of indoor spaces where people spend lots of time (https://wwwnc.cdc.gov/eid/article/26/7/20-0764_article …, https://wwwnc.cdc.gov/eid/article/26/8/20-1274_article …). Summer should improve this. 6/10

        31 replies 216 retweets 1,109 likes
        Show this thread
      7. Trevor Bedford‏Verified account @trvrb 30 Apr 2020

        However, given that Rt nationally is at the moment ~1, I don't see why we expect large declines in daily case counts over the next month, given that behavior has been pretty static, or perhaps rising. Figure from https://www.apple.com/covid19/mobility …. 7/10pic.twitter.com/zKnqXOOzjH

        24 replies 276 retweets 1,265 likes
        Show this thread
      8. Trevor Bedford‏Verified account @trvrb 30 Apr 2020

        I would suspect that the dynamic we're looking at is local policy decisions / people's changing behavior as risk is perceived to decrease resulting in increasing local case counts and then a cycle of increased social distancing to compensate. 8/10

        8 replies 158 retweets 1,005 likes
        Show this thread
      9. Trevor Bedford‏Verified account @trvrb 30 Apr 2020

        There may well be cities / counties that achieve suppression locally, but nationally I expect things be messy with flare-ups in various geographies followed by responses to these flare-ups. 9/10

        13 replies 187 retweets 1,161 likes
        Show this thread
      10. Trevor Bedford‏Verified account @trvrb 30 Apr 2020

        Trevor Bedford Retweeted Trevor Bedford

        If we continue at our current pace of perhaps ~300k infections per day (https://twitter.com/trvrb/status/1249414308355649536 …). The US would have very roughly 50M cumulative infections by September 1 and be at ~15% population immunity. 10/10

        Trevor Bedford added,

        Trevor BedfordVerified account @trvrb
        Estimating total number of infections is difficult without serology (see this thread: https://twitter.com/trvrb/status/1247609734896607232 …), but I'd guess that we're catching between 1 in 10 to 1 in 20 infections as a confirmed case. 14/18
        Show this thread
        72 replies 300 retweets 1,154 likes
        Show this thread
      11. Trevor Bedford‏Verified account @trvrb 30 Apr 2020

        I'd be happy to wrong here and start to see a week-over-week decline. I just don't know what gets us there if we're not there already.

        62 replies 121 retweets 1,325 likes
        Show this thread
      12. Trevor Bedford‏Verified account @trvrb 30 Apr 2020

        An important subtlety I missed in the original thread: Tests per day almost doubled from ~120k to ~200k over the course of April while confirmed cases remained roughly flat at ~30k per day. Does suggest some decrease in number of infections, though probably less than than 1.6X.

        62 replies 151 retweets 1,274 likes
        Show this thread
      13. End of conversation

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