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trvrb's profile
Trevor Bedford
Trevor Bedford
Trevor Bedford
Verified account
@trvrb

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Trevor BedfordVerified account

@trvrb

Scientist @fredhutch, studying viruses, evolution and immunity. Collection of #COVID19 threads here: https://bedford.io/misc/twitter/ 

Seattle, WA
bedford.io
Joined December 2010

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    1. Trevor Bedford‏Verified account @trvrb 12 Mar 2020

      I very respectfully disagree with the estimate of 100k #COVID19 infections in Ohio put forth by the @OHdeptofhealth. As far as I can ascertain from the press coverage (https://www.news5cleveland.com/news/continuing-coverage/coronavirus/ohio-department-of-health-says-100-000-ohioans-are-carrying-coronavirus …), this number comes from extrapolating from 2 community cases detected. 1/5

      136 replies 770 retweets 1,859 likes
      Show this thread
    2. Trevor Bedford‏Verified account @trvrb 12 Mar 2020

      A couple simple ways to think about this estimate. On one hand, we believe that Wuhan had roughly 100k infections on Feb 1 (via @MRC_Outbreak report 7 https://www.imperial.ac.uk/mrc-global-infectious-disease-analysis/news--wuhan-coronavirus/ …). 2/5

      8 replies 35 retweets 213 likes
      Show this thread
    3. Trevor Bedford‏Verified account @trvrb 12 Mar 2020

      Wuhan as a city had seen 1000 severe cases and 300 deaths at this point (https://covid2019.azurewebsites.net/ ). Thus, given the severity of this disease I don't see how it's possible to reach 100k infections and not notice it in deaths and hospitalizations. 3/5

      22 replies 48 retweets 520 likes
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    4. Trevor Bedford‏Verified account @trvrb 12 Mar 2020

      Another way to look at this is that it took the virus from ~Nov 1 to Feb 1 to reach 100k infections in Wuhan. This is ~90 days. Thus, it would have had to have been circulating in Ohio since mid-Dec for this to be the case, which is almost certainly not the case. 4/5

      27 replies 48 retweets 384 likes
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      Trevor Bedford‏Verified account @trvrb 12 Mar 2020

      I don't doubt community spread is happening Ohio and it's highly difficult to do these prevalence estimates well without wider surveillance efforts, but I think this is certainly a strong overestimate. 5/5

      7:28 PM - 12 Mar 2020
      • 45 Retweets
      • 404 Likes
      • Vivek Singha Todd Ga tess Liz Lawson Heather Champion ™️ Debbie Alex Naka Fernando Cesar Really? 🙄
      18 replies 45 retweets 404 likes
        1. New conversation
        2. Trevor Bedford‏Verified account @trvrb 12 Mar 2020

          I'm basing their logic on this quote: "Whenever you know of 2 people that have it due to community spread, then you can assume that 1% of your population has it," said ODH Press Secretary Melanie Amato, citing a 2017 Morbidity and Mortality Weekly Report from the CDC."

          28 replies 63 retweets 356 likes
          Show this thread
        3. Trevor Bedford‏Verified account @trvrb 12 Mar 2020

          A follow up based on responses. Many people are saying there's a huge amount of uncounted mortality due to pneumonia. The @CDCgov tracks this, and we don't yet see this in the data (https://www.cdc.gov/flu/weekly/#S2 ). I expect #COVID19 to start to show up here, but it hasn't yet.pic.twitter.com/D5mOVEfMMX

          38 replies 157 retweets 545 likes
          Show this thread
        4. End of conversation
        1. New conversation
        2. Scheplick‏ @scheplick 12 Mar 2020
          Replying to @trvrb

          At this point, overestimating is better

          1 reply 0 retweets 3 likes
        3. eigen道‏ @eigentao 12 Mar 2020
          Replying to @scheplick @trvrb

          Disagree. If you overestimate then the math suggests a much lower death rate which leads to dismissal as just another flu

          0 replies 0 retweets 2 likes
        4. Show replies
        1. New conversation
        2. Armen Berjikly‏Verified account @armenberjikly 12 Mar 2020
          Replying to @trvrb

          Couldn’t it have been achieved through multiple patient zeros kicking off multiple clusters ? Seattle and wuhan were single source from what we can tell.

          1 reply 0 retweets 3 likes
        3. Armen Berjikly‏Verified account @armenberjikly 12 Mar 2020
          Replying to @armenberjikly @trvrb

          Not saying I believe this but isn’t it a plausible way to get to 100k in this amount of time ?

          1 reply 0 retweets 4 likes
        4. Show replies
        1. MattDog‏ @MattDog_2020 12 Mar 2020
          Replying to @trvrb

          To be honest. First over estimate in the entire epidemic. That’s really who you want to bring the hammer on?

          0 replies 0 retweets 2 likes
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        1. eigen道‏ @eigentao 12 Mar 2020
          Replying to @trvrb

          Agree, It’s impossible. Even a doubling rate of three days means that there were 1500 cases 18 days ago, and that would mean at least 5-15 deaths observed. And that’s extreme doubling.

          0 replies 0 retweets 2 likes
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        1. JF‏ @jackfruitstaken 12 Mar 2020
          Replying to @trvrb

          If it's a calculated lie it could be a masterstroke of public health policy

          0 replies 0 retweets 1 like
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        1. Vylar Kaftan, the Cassandra of Covid‏ @Vylar_Kaftan 12 Mar 2020
          Replying to @trvrb

          I'd call it a very high estimate indeed, but plausible. I don't think it's more than that, but it could be that high--if the estimate is meant to add in a "buffer" to account for all the people who are only mildly sick or asymptomatic.

          0 replies 0 retweets 4 likes
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