We see that all six of these viruses cluster quite closely into a distinct clade. This suggests limited genetic diversity in the source of exposure. 2/4pic.twitter.com/s9FItd0E77
U tweetove putem weba ili aplikacija drugih proizvođača možete dodati podatke o lokaciji, kao što su grad ili točna lokacija. Povijest lokacija tweetova uvijek možete izbrisati. Saznajte više
We see that all six of these viruses cluster quite closely into a distinct clade. This suggests limited genetic diversity in the source of exposure. 2/4pic.twitter.com/s9FItd0E77
However, these 6 genomes are not identical. 5 are highly similar and differ between 0 and 10 mutations, while 1 is more diverged. 3/4pic.twitter.com/Oa2osxf8cK
A reproducible pipeline to generate these results is openly available at https://github.com/blab/sars-like-cov …. 4/4
Some further notes:
1. Recombination doesn't seem to be much of an issue for the Wuhan clade. They group across 2kb windows as @richardneher shows here:https://twitter.com/richardneher/status/1216402670514294785 …
2. The apparent ~55nt divergence of BetaCoV/Wuhan/IVDC-HB-05/2019 relative to the other 5 may be due to sequencing artifacts as @arambaut notes here:https://twitter.com/arambaut/status/1216502311918481408 …
We've updated the analysis to be more stringent about SNPs. See here for discussion: http://virological.org/t/initial-genome-release-of-novel-coronavirus/319/9?u=trvrb ….
What are seq designations of the nCoV (6 genomes) in the fasta file? I don’t see the same designations
In adhering to GISAID Terms of Use, we're not allowed to re-share sequences and so raw sequence data is not present in the FASTA. In the readme here https://github.com/blab/sars-like-cov#data … I describe how the six genomes need to be added manually after download from GISAID.
I de dkmjmux x u u
Twitter je možda preopterećen ili ima kratkotrajnih poteškoća u radu. Pokušajte ponovno ili potražite dodatne informacije u odjeljku Status Twittera.