Thomas Macrina

@tmacrina

CS graduate student @ Princeton; connectomes

Princeton, NJ
Vrijeme pridruživanja: veljača 2009.

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  1. proslijedio/la je Tweet
    25. sij

    What an exciting couple of months for the field of connectomics! Thought it would be good to post a thread that captures recent progress--

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  2. proslijedio/la je Tweet
    22. sij

    Proud to introduce "hemibrain" : a connectome of the Drosophila central brain. . Please see overview website: Play with data on neuPrint:

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  3. proslijedio/la je Tweet
    20. sij

    I am very excited, to finally share this: Using a functional approach we uncovered a mechanism for whitening, a fundamental computation that decorrelates neuronal population activity for pattern classification by memory networks.

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  4. proslijedio/la je Tweet
    15. sij

    New on synapse-resolution reconstruction of motor control circuits in the Drosophila ventral nerve cord (VNC) led by , , and Brett Graham. A great collaboration with the labs of & . 1/n

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  5. proslijedio/la je Tweet
    14. sij

    Ground breaking: The construction work for 's new high-throughput TEM facility has started. We are building a next-generation serial-section TEM suite with an imaging capacity of >3TB/hour for petabyte-scale neuronal circuit reconstruction.

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  6. proslijedio/la je Tweet
    13. sij
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  7. proslijedio/la je Tweet
    10. sij

    Last year we held the DeepMath 2019 conference in NYC. Now the talks are up online for all to view!

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  8. 2. sij

    TLDR: Network models in neuro/AI commonly assume continuously variable synapses. We show that sizes of synapses between L2/3 pyramidal cells (PyCs) are primarily binary, and these binary states are correlated for multi-synaptic connections. 2/n

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  9. 2. sij

    HNY and 1st discovery from mouse V1 serial section EM dataset! Largest wiring diagram yet btw identified cortical neurons Brain Science supported by MICrONS. 1/n

    Ovo je potencijalno osjetljiv multimedijski sadržaj. Saznajte više
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  10. proslijedio/la je Tweet
    13. pro 2019.

    Automatic prediction of synaptic links in a whole Drosophila brain: Read about 's method in our preprint, result of a fruit(fly)ful collaboration with the labs of , , , and !

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  11. proslijedio/la je Tweet
    27. stu 2019.

    How do our brains rewire as we develop from babies (with overconnected neurons) into adults (with the "right," refined neural circuitry)? In this week, we use electron microscopy to uncover details about how this happens in the cerebellum:

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  12. proslijedio/la je Tweet
    3. lis 2019.

    Hey! Look at this! Fast automated TEM for collecting more pixels than you could shake a stick at!

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  13. proslijedio/la je Tweet
    3. lip 2019.

    Another great piece from the Lee lab: Automated section collection on to grid tape enables high-throughput serial section TEM.

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  14. proslijedio/la je Tweet
    30. svi 2019.

    We’re excited to present a collab between HMS (, , C-L.Chen, ) & the European Synchrotron ( and P.Cloetens) utilizing state-of-the-art X-ray imaging tech to image neurons at nanoscale resolution over mm lengths. 1/6

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  15. proslijedio/la je Tweet
    4. svi 2019.

    Saturday Science: my paper on biorXiv shows how image volumes made from electron microscopy can be used to reveal info about what happens as neurons rewire during normal brain development.

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  16. proslijedio/la je Tweet
    9. sij 2019.

    Wondering what is good for? Specific disynaptic inhibitory motifs promote decorrelation and variance normalization of neuronal population activity, revealed by functional and structural in the olfactory bulb.

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  17. proslijedio/la je Tweet
    6. stu 2018.

    Want to learn about the synaptic scale organization of the oculomotor system? Come stop by II9 today at

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  18. 4. stu 2018.

    Want to noodle on why the rate an axon touch converts to a synapse for pyramidal spine heads is similar to interneuron dendrites in mouse cortex? Stop by today at 1PM, . One of the many connectomics posters from lab & team!

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  19. proslijedio/la je Tweet
    1. stu 2018.

    Look for all 10 posters from Lab at , ranging from retinal cells mapped in to zebrafish hindbrain from and of course petascale connectomics with our collaborators at !

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  20. proslijedio/la je Tweet
    1. stu 2018.

    Interested in linking structure, function and computation in cortex? Together with our wonderful collaborators we have 17 presentations at including recording from ~100K neurons in 1mm^3 and use to dissect brain function (sessions: 219, 519, 699, 767, 088)

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