Maybe defense ops maturity is a factor also. Does Tavis need AV in his Google Beyondcorp environment? Probably not. Do many of us need it to protect environments full of legacy and security compromises? Yes. At least maybe. Big difference in which AV also.
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Windows defense is getting better at mitigations outside of traditional AV especially, for AV it doesnt do much though from the tests I've seen over the last few years. To you the trad-AV part of Defender works?
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I really think you're confused about what whitelisting is.
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What are the constraints offered here by whitelisting to all of you? Where does the value-add lie and what are the limitations?
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What are you trying to stop: Malicious powershell scripts? Of course whitelisting can prevent that. An authorized but malicious user doing authorized but malicious things with powershell? Whitelisting can't stop that, but neither can Antivirus.
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