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SteveJoffe's profile
Steve Joffe
Steve Joffe
Steve Joffe
@SteveJoffe

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Steve Joffe

@SteveJoffe

Research ethics, pediatric ethics, cancer ethics, genomethics, science policy @ UPenn. Grateful immigrant. Speak only for myself. R/Ts≠likes. He/him.

Philadelphia, PA
medicalethics.med.upenn.edu/people/faculty…
Joined June 2011

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    Steve Joffe‏ @SteveJoffe 13 Mar 2018

    Steve Joffe Retweeted Kaiser Health News

    1/ This remains a jaw-dropping story. There's actually an important conceptual thread running to #RightToTry. Let me explain.https://twitter.com/KHNews/status/973662127725694976 …

    Steve Joffe added,

    Kaiser Health NewsVerified account @KHNews
    Three people injected with an unauthorized #herpes vaccine by a Southern Illinois University researcher have filed suit against his company. via #KHNews @marisaataylor https://khn.org/ODIxNTM0  #bioethics
    4:58 PM - 13 Mar 2018
    • 17 Retweets
    • 20 Likes
    • Sarah Sparky not “Bad Patch” Bob Marilyn Mann Ross McKinney Jr, MD Sandra Dial Quentin Dubé Eagan Kemp Dr. Alison Bateman-House Norton
    1 reply 17 retweets 20 likes
      1. New conversation
      2. Steve Joffe‏ @SteveJoffe 13 Mar 2018

        2/ This study should have been overseen by the @US_FDA, but by all appearances Rational Vaccines flouted the rules and went forward without oversight.

        1 reply 1 retweet 7 likes
        Show this thread
      3. Steve Joffe‏ @SteveJoffe 13 Mar 2018

        3/ Why? Because its founders & scientists didn't accept the important role of the FDA in therapeutic development and validation--they saw it instead as a ponderous bureaucratic obstacle to validating treatments and getting them to patients.

        1 reply 1 retweet 7 likes
        Show this thread
      4. Steve Joffe‏ @SteveJoffe 13 Mar 2018

        4/ The same perspective informs #RightToTry; it views the @US_FDA as a bureaucratic obstacle that stands between patients and the drugs that might cure them.

        2 replies 1 retweet 6 likes
        Show this thread
      5. Steve Joffe‏ @SteveJoffe 13 Mar 2018

        5/ The common thread is efforts, from a "libertarian" perspective, to delegitimize the @US_FDA. (I put libertarian in quotes because I'm skeptical that the main motivation is deeply held philosophical belief)

        2 replies 1 retweet 6 likes
        Show this thread
      6. Steve Joffe‏ @SteveJoffe 13 Mar 2018

        6/ I'm profoundly relieved that #RightToTry failed tonight, because if these efforts to delegitimize the @US_FDA take hold, we will see many more cases of unscrupulous actors offering "treatments" and "trials" that are really about making a buck.

        1 reply 9 retweets 22 likes
        Show this thread
      7. Steve Joffe‏ @SteveJoffe 13 Mar 2018

        7/ That's why efforts to defend the @US_FDA are so important if you care about patients and the public health. /end

        1 reply 3 retweets 11 likes
        Show this thread
      8. Steve Joffe‏ @SteveJoffe 14 Mar 2018

        postscript/ There are legitimate arguments about how the @US_FDA should balance access vs. rigorous evaluation. https://jamanetwork.com/journals/jama/article-abstract/900544 …

        1 reply 0 retweets 0 likes
        Show this thread
      9. Steve Joffe‏ @SteveJoffe 14 Mar 2018

        PS2/ I happen to have a conservative view, but respect the arguments of those who believe otherwise. It's the fundamental rejection of the concept that drugs should be shown to have efficacy that justifies their risks that most troubles me.

        0 replies 0 retweets 1 like
        Show this thread
      10. End of conversation

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