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Devil is in the detail 3 - Stratification - https://onein300.com/2019/09/20/narrowing-and-widening-the-target-stratification/ … #alsmndsymp #ALSSymp #als #mnd
I believe what you are describing is actually just exclusion criteria. “Stratification“ is typically groupings of patients within the trial. This is typically done to ensure balance when you have a heterogeneous sample.
No I describe stratification whether it be by expected prognosis, arbitary group or other. I don’t focus on trial exclusion.
What you describe in the nurown and sod1 trials is the use of exclusion criteria. Stratification in brainstorm would be equally allocating rapid and slow progressors to each of the treatment arms.
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