Here's what I currently know about the MASpocalypse. For some customers, only workaround is to use direct downloads. http://c-command.com/blog/2015/11/12/mac-app-store-versions-of-apps-not-launching/ …
@mjtsai Including the restart? If so I strongly suspect a Layer 8 failure.
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@siegel Yes, including multiple restarts (they say).
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Michael Tsai
Lich Bleach-Skull