Shalek Lab

@shaleklab

Alex K. Shalek Lab ////. Genomics, immunology, systems biology.

Cambridge, MA
Vrijeme pridruživanja: studeni 2019.

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  1. proslijedio/la je Tweet

    NEW Review: Distribution and storage of inflammatory memory in barrier tissues

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  2. 3. velj

    Our review on inflammatory memory in barrier tissues with now out in !

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  3. proslijedio/la je Tweet
    3. velj

    The lab's first ideas out on paper. Thanks to Semir, Seth, and . With important contributions from the first PhD students and postdocs to join on this adventure!

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  4. 28. sij

    Our new paper on the development of broadly neutralizing antibodies in HIV-1 controllers with the Yu, Lichterfeld, and labs now out in !

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    26. sij

    Will have full thoughts later when I can form coherent sentences, all I can say right now is how incredibly lucky and privileged I am to have been a part of this ❤️

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  6. proslijedio/la je Tweet
    25. sij

    Hosting immunology students for interview weekend at Harvard. So much talent and diversity from around the world in town. Future is very bright for immunology.

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    21. sij

    In a promising step toward infection treatment and prevention, research from , , and has found a master regulator needed for the Toxoplasma gondii parasite to chronically infect a host.

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    19. sij

    News & Views: A paper in Nature shows that near-complete protection from tuberculosis infection can be conferred using a century-old vaccine, simply by changing its route of administration.

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    19. sij

    Our other TA, Vincent, leading a session on single cell genomics - as a grad student in , we think he's well prepared for this!

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    Not all heroes wear capes.

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  11. proslijedio/la je Tweet
    16. sij

    The T. gondii parasite can transition between acute and chronic forms to avoid immune clearance. In a new study led by , and identify a transcription factor that allows the parasite to make this switch.

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    To shed light on changes in gene expression during differentiation and cell cycle progression, the researchers performed a first of its kind single-cell RNA sequencing of Toxoplasma gondii in collaboration with members of Alex Shalek’s lab .

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  13. proslijedio/la je Tweet
    16. sij

    I'm excited to share our paper on the regulation of chronic infection! Many thanks to all the members of the and to our collaborators in the for their help applying single-cell RNA-sequencing to this fascinating parasite.

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    13. sij

    Both and Alter lab have highlighted the importance of looking beyond the antigen - Alter with adjuvants in flu vaccine and Shalek on how you deliver TB vaccine. (Alter) (Shalek)

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    7. sij

    In 2019, four of our researchers - Bruce Walker, Dennis Burton, Galit Alter, and - made 's Highly Cited Researcher list. Here's to an even bigger impact in 2020!

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    6. sij
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    3. sij
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  18. proslijedio/la je Tweet
    2. sij

    It’s only Jan 2nd and already one of the years remarkable stories is published...good reminder that sometimes innovation is seeing the same thing everyone else has and thinking about it differently.

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  19. proslijedio/la je Tweet
    2. sij

    TB NEWS: Changing the route of immunization dramatically improves protective power of century-old . Studies in animals by scientists published in .

    Lungs of animals vaccinated with TB vaccine
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  20. proslijedio/la je Tweet
    2. sij

    9/10 IV BCG vaccinated macaques were protected from TB challenge - a game changer in TB vaccine! Also check out how single-cell transcriptome mapped T cell responses.

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