It’d be great to observe what motor cortical populations do during speaking with single-neuron resolution, but how? There’s no direct animal model, and intracortical recording requires surgery. 2/
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Neural dynamics motif #2: Strong rotatory dynamics are present during speech production. Here we applied the methods of Churchland, Cunningham et al 2012:pic.twitter.com/cVh5CKQgx1
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Why this is the case is a fascinating open question. It may be that if these are effective computational strategies for generating the right muscle commands for arm and hand movements, then they’re also well-suited for generating speech-producing muscle commands. 14/
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Another open question is whether finding this activity in "arm" motor cortex is due to remapping because of the participants' tetraplegia. We don't think this is the case, but a definite answer is elusive because we'd need intracortical recording in able-bodied people. 15/15
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| AP Giannini, Burroughs Wellcome CASI, Stanford Wu Tsai Postdoc Fellow