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AAT is commonly diagnosed in middle-aged folk after they've developed COPD or emphysema. There's about 100,000 people in the US with AAT, with only 10,000 of those actually diagnosed. It's more common for those with Northern European and Iberian ancestry.
If you suspect that you or a loved one has AAT, then you can get an easy blood test to measure the levels of antitrypsin in your blood. If you are diagnosed then all it requires is an annual antitrypsin blood, liver function, and pulmonary function test.
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