he/him 
I'm finding that most CSS-in-JS libraries aren't radical and strict enough. Ban descendent selectors, whitelist pseudo selectors, don't allow dynamic values. What I really want is just styles-in-JS. Get rid of the cascade.
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If your motivation for using css in js is to remove the cascade, why not just write stricter css?
When you write CSS you still need to deal with specificity issues. I don't want to worry about correctly namespacing all of my styles. Colocation of styles with your component code is generally good. Changes are isolated to one place, dead code is removed easily.
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no cascade, classes only, css file compiles into two files, file.js (names hashed content of the class) + file.css (classes renamed to a hash of their content)
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I agree, although there is some tooling that can alleviate this.
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