Science Signaling

@scisignal

Uncovering mechanisms in biology, gaining insights into physiology and disease.

Washington, DC
stke.sciencemag.org
Vrijeme pridruživanja: travanj 2010.
1.648 fotografija ili videozapisa Fotografije i videozapisi

Tweetovi

Blokirali ste korisnika/cu @scisignal

Jeste li sigurni da želite vidjeti te tweetove? Time nećete deblokirati korisnika/cu @scisignal

  1. Prikvačeni tweet
    28. sij

    In this week’s issue of Science Signaling, new studies reveal that some commonly used antibodies can fail to bind to their target proteins, depending on biochemical context.

    13 proslijeđenih tweetova 40 korisnika označava da im se sviđa
    Poništi
  2. prije 11 sati

    Schüchner, Ogris, and colleagues find that a widely used Myc-specific antibody may not fully recognize Myc-tagged proteins, depending on sequences adjacent to the tag.

    2 proslijeđena tweeta 3 korisnika označavaju da im se sviđa
    Poništi
  3. prije 15 sati

    New research that highlights the shortcomings of antibodies suggests that scientists may want to re-evaluate data gathered using some commercial antibody kits.

    3 proslijeđena tweeta 3 korisnika označavaju da im se sviđa
    Poništi
  4. 2. velj

    Bye, Mahaut-Smith, and colleagues intricately visualize how calcium waves stimulated by purinergic receptors coordinate binding in megakaryocytes.

    3 proslijeđena tweeta 10 korisnika označava da im se sviđa
    Poništi
  5. 1. velj

    The Davis lab finds that genetic diversity in inhibitory receptors impacts membrane proximal signaling and the formation of activating immune synapses. .

    1 korisnik označava da mu se sviđa
    Poništi
  6. 31. sij

    Flanking amino acids can disturb how the common research antibody recognizes Myc-tagged proteins.

    5 proslijeđenih tweetova 6 korisnika označava da im se sviđa
    Poništi
  7. 31. sij

    These animations demonstrate how adjacent amino acid sequences (1-2) and posttranslational modifications in proteins (3-4) can affect or impair how two research monoclonal recognize their targets in a protein.

    29 proslijeđenih tweetova 69 korisnika označava da im se sviđa
    Poništi
  8. 31. sij

    Widely used antibodies against the catalytic subunit of PP2A are sensitive to methylation and fail to immunoprecipitate some holoenzymes, shows a new study from the Ogris lab.

    1 reply 8 proslijeđenih tweetova 15 korisnika označava da im se sviđa
    Poništi
  9. 28. sij

    New results suggest that redox regulation of residues may be determined by changes in the conformations of target proteins that occur in a pathway-specific manner.

    3 proslijeđena tweeta 7 korisnika označava da im se sviđa
    Poništi
  10. 27. sij

    Don’t miss this new Focus from Tammie Bishop and Peter Ratcliffe! These authors discuss a study that reveals how glomus cells in the carotid body acutely respond to .

    4 proslijeđena tweeta 4 korisnika označavaju da im se sviđa
    Poništi
  11. 27. sij

    In rat megakaryocytes, patterns in calcium ion waves activate and polarize integrins in a manner dependent on two purinergic receptors.

    26 proslijeđenih tweetova 93 korisnika označavaju da im se sviđa
    Poništi
  12. 26. sij

    A new study suggests that HIF2α target gene expression may set the carotid body’s acute ability.

    2 proslijeđena tweeta 1 korisnik označava da mu se sviđa
    Poništi
  13. 24. sij

    The Barneo lab at finds that the transcription factor HIF2α is necessary for glomus cells to acutely respond to .

    1 proslijeđeni tweet 2 korisnika označavaju da im se sviđa
    Poništi
  14. 24. sij

    The Held lab shows how epidermal growth factor exposes cryptic cysteine residues to by altering the conformation of target proteins.

    3 korisnika označavaju da im se sviđa
    Poništi
  15. 23. sij

    In a new study, Bye, Mahaut-Smith and colleagues intricately visualize how calcium waves stimulated by purinergic receptors coordinate binding in megakaryocytes.

    5 proslijeđenih tweetova 11 korisnika označava da im se sviđa
    Poništi
  16. 21. sij

    Check out this week’s new issue of Science Signaling! Including how waves of calcium activate platelet integrins, redox regulation of cysteine residues, and how glomus cells respond to a lack of oxygen.

    7 proslijeđenih tweetova 16 korisnika označava da im se sviđa
    Poništi
  17. 21. sij

    Why is typically a non-inflammatory disease? Researchers discover that the effector domains of the "cluster bomb" toxin MARTX coordinate to damage intestinal cells while silencing the inflammatory response.

    2 proslijeđena tweeta 3 korisnika označavaju da im se sviđa
    Poništi
  18. 20. sij

    Ligand binding triggers the and clustering of TNFR1 monomers and dimers into trimers and higher-order oligomers.

    2 korisnika označavaju da im se sviđa
    Poništi
  19. 20. sij

    The common chemotherapy can promote the migration of cancer cells through phosphorylation of a translation factor, shows the Willis lab at .

    1 proslijeđeni tweet
    Poništi
  20. 19. sij

    A comprehensive study reveals how the kidneys of rats undergo metabolic shifts during the early stages of diet-induced and kidney damage.

    1 proslijeđeni tweet 2 korisnika označavaju da im se sviđa
    Poništi

@scisignal još nije objavio nijedan Tweet.

Čini se da učitavanje traje već neko vrijeme.

Twitter je možda preopterećen ili ima kratkotrajnih poteškoća u radu. Pokušajte ponovno ili potražite dodatne informacije u odjeljku Status Twittera.

    Možda bi vam se svidjelo i ovo:

    ·