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This woman is beyond contempt. David Leakey couldn’t possible be bullied because he’s a privileged white male? https://twitter.com/hackneyabbott/status/1224975173570453505 …
Tweet je nedostupan.Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
David Grainger proslijedio/la je Tweet
Apply to Panacea Stars Develop 2020 before 23rd Feb :http://panacea-stars.com/develop
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Turning Karl Marx back on himself, socialism really is the opium of the people. Superficially attractive, but utterly destructive. I always viewed Ayn Rand’s Atlas SHrugged as Reductio Ad Absurdum - but nearer than i sver imagined possible
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There is much to dislike about
@realDonaldTrump - but listening to his speech, the contrast between a successful US and a sclerotic#EU is thrown into sharp relief: American culture has never been posioned by socialismPrikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
David Grainger proslijedio/la je Tweet
The #1 cause of startup death is making something no one wants. The #2 cause is spending too much. Those two account for so many deaths that I'm not even sure what #3 is. If you merely make something people want and don't spend too much, you're way ahead.
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It’s interesting that people think it’s unreasonable if don’t to offer a vegan menu choice - why is it acceptable not to have a NON-vegan choice? I’m an obligate meat eater!https://twitter.com/danwootton/status/1224102063757545472 …
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And then, when you have read that, read this
#DrugBaron piece on False Discovery Rates if you havent already: http://drugbaron.com/why-too-many-clinical-trials-fail-and-a-simple-solution-that-could-increase-returns-on-pharma-rd/ … - because even with a correct definition p values can be exceptionally misleading in real-world use when testing many hypothesesPrikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
This thread is worth a read if you work in clinical trials (or any other branch of science) and feel at all hazy aboiut what the p value tells you. Your life’s work depends on interpreting them correctly, so you better be ABSOLUTELY clear what it means!https://twitter.com/FSingletonThorn/status/1223056191548342273 …
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Because “activity in a subset” is not activity unless the trial was designed to look for that. This fundamental misunderstanding of statistics lies at the heart of the debatehttps://twitter.com/jbemis007/status/1223451077376262144 …
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Agree with all theee observations in this threadhttps://twitter.com/wreeve/status/1223289615047712768 …
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Key point. We don’t need to raise incentives but lower barriers, as I explained in this
@PanaceaInnov blog last year: https://medium.com/panaceastars/promoting-innovation-is-more-about-removing-barriers-than-increasing-incentives-a576c17f0c1b …https://twitter.com/rodolfor/status/1223292142153555968 …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi
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David Grainger proslijedio/la je Tweet
“I am not able to arrange any divestment at short notice. But I can arrange for the gas central heating in college to be switched off,” St John’s College principal bursar Adrew Parker tells students demanding divestment from oil companies.https://www.thetimes.co.uk/article/professor-at-st-johns-college-oxford-turns-oil-row-into-a-heated-debate-0zr2wpmb5 …
Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
David Grainger proslijedio/la je Tweet
Really cool paper from the labs of Simon Cook, Nicholas Ktistakis and Oliver Florey
@BabrahamInst about the regulation of#autophagy in mitotic cells. See comment below for a link to my@F1000Prime recommendation.https://twitter.com/MolecularCell/status/1217957084089634816 …Prikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
For a century before social media arguments were built principally around the “facts”. Today, arguments are built around convenient claims that are not immediately disprovable
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The rise of the grey zone of truth: what social media has done in the last decade is move the national debate firmly into the grey zoen - about things that are neithe provably true or clearly falsifiable
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When I write this
#DrugBaron piece in 2015 (“DMD Drugs: An Existential Crisis for FDA?” http://drugbaron.com/dmd-drugs-an-existential-threat-to-the-fda/ … it was exactly the current situation - with endless approved cancer drugs that dont work and the possibility of an aducanumab approval - that I was envisagingHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Or put that another way: does making money trump doing good (again)? If we answer yes, maybe we can see why the public has lost faith in pharma - even if they don’t understand the details of what is going on here
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Raises question: if
$BIIB manage to get aducanumab approved despite it not working, does that mean management were smart to keep going (rather than dumb, as I have suggested previously)?Prikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
I think the FDA is in danger of losing the plot entirely. Which is why I think they might actually approve aducanumab
$BIIBPrikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi
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