Martin Sauvageau

@sauvagem1

Assistant Professor , lncRNAs and Noncoding Genome in Development & Disease

Montréal, Québec
Vrijeme pridruživanja: kolovoz 2014.

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  1. proslijedio/la je Tweet
    3. velj

    Condolences to Phil Leder's family and worldwide colleagues. He made groundbreaking contributions on the genetics of cancer and aging. This is a sad day for science.

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  2. proslijedio/la je Tweet
    30. sij

    We are recruiting! Want to work on and make a meaningful contribution to changing the story of this disease? Interested in cell biology? Send me your CVs!

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    The n-Lorem Foundation intends to form the connective tissue between patients, researchers, facilities and regulators needed to supply individual patients with RNA therapies designed to treat their own ultra-rare disease—at no cost

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  4. proslijedio/la je Tweet
    25. sij

    Following a few requests, here’s the (now-required) Twitter summary of our paper on 'transcriptional scanning' in the testes.

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    17. sij

    A Conserved Noncoding Locus Regulates Random Monoallelic Xist Expression across a Topological Boundary

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  6. proslijedio/la je Tweet
    13. sij

    Structure-Specific Cleavage of an RNA Repeat Expansion with a Dimeric Small Molecule Is Advantageous over Sequence-Specific Recognition by an Oligonucleotide | ACS Chemical Biology

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    9. sij

    Fantastic opportunity Pharma — Senior genome scientist ! This team is inspiring and the one behind first treatment for — Ionis has truly transformed !

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    7. sij

    Pleased to present Jong-Sun Lee's work showing that antisense knockdown causes transcription termination. These reagents cannot be used in isolation to establish an RNA-mediated function for noncoding RNA loci!

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  9. proslijedio/la je Tweet
    7. sij

    If you thought an ASO phenotype *proves* an RNA function, think again (and read this from and back-to-back one from ). Even better - develop a method that works well and allows distinguishing! We need one...

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  10. 7. sij

    Important for anyone using ASO to knockdown lncRNA

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    7. sij
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  12. proslijedio/la je Tweet
    4. sij

    two outstanding recent reviews on the arms race between mobile genetic elements and host defense systems. inspiring read. Eugene Koonin and colleagues: and colleagues:

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    3. sij
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    2. sij

    Super pleased that our work identifying a new lncRNA tumour suppressor gene in melanoma is now out. Great way to start the New Year.

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  15. 29. pro 2019.

    Pretty good day: Skiing, beers and catching up with at the summit

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  16. proslijedio/la je Tweet
    20. pro 2019.

    I highly recommend these tutorials if you want to get into analysis of nanopore data. They are some of the best I’ve seen. Thanks for making them publicly available.

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  17. proslijedio/la je Tweet
    20. pro 2019.

    So, and what do you think? Isn't it time to up the game and put Canada back on top as an international leader in research and innovation? We have so much talent but so little funding. Let's make 2020 the year we get back on track.

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  18. 20. pro 2019.

    Fun lab outing before the holidays: curling, korean food and craft beers. I am lucky to work with these guys!

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  19. proslijedio/la je Tweet

    Overcoming challenges and dogmas to understand the functions of pseudogenes by , and Key points in

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  20. proslijedio/la je Tweet
    16. pro 2019.

    Old pipelines called anything without >100aa ORF lncRNA; tools like RNAcode or PhyloCSF easily call these as coding genes, and this is what they should be called, these are not lncRNAs! There is evidence 'real' lncRNAs are translated, but little evidence for functional products

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