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sarahdoingthing's profile
Sister Sarah
Sister Sarah
Sister Sarah
@sarahdoingthing

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Sister Sarah

@sarahdoingthing

~cryptosalience~ contributing editor of http://ribbonfarm.com  ~~~~read Christopher Alexander, do rituals~~~~

Joined September 2013

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    1. Sister Sarah‏ @sarahdoingthing 19 Jan 2014
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      A subpopulation of sociopaths is GTO for social organisms, but a subpopulation of autists might be GTO for a social culture @DoTheWeirdStuff

      2 replies 0 retweets 1 like
    2. St. Rev  ☯️ 🏴 😻‏ @St_Rev 19 Jan 2014
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      Replying to @sarahdoingthing

      @sarahdoingthing @DoTheWeirdStuff What is GTO?

      1 reply 0 retweets 0 likes
    3. Sister Sarah‏ @sarahdoingthing 19 Jan 2014
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      Replying to @St_Rev

      @St_Rev @DoTheWeirdStuff sorry "game theory optimal" too many characters but the car is nice too

      1 reply 0 retweets 1 like
    4. St. Rev  ☯️ 🏴 😻‏ @St_Rev 19 Jan 2014
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      Replying to @sarahdoingthing

      @sarahdoingthing @DoTheWeirdStuff So some analogy to cooperator/defector equilibria in iterated prisoner's dilemma?

      1 reply 0 retweets 0 likes
    5. Sister Sarah‏ @sarahdoingthing 19 Jan 2014
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      @St_Rev @DoTheWeirdStuff Some kind of iterated game theory but not necessarily along cooperate/defect lines, yes totally.

      3 replies 0 retweets 0 likes
    6. St. Rev  ☯️ 🏴 😻‏ @St_Rev 19 Jan 2014
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      Replying to @sarahdoingthing

      @sarahdoingthing @DoTheWeirdStuff ...bacteria lost genes for DNA repair because a higher mutation rate was selected for.

      1 reply 0 retweets 1 like
    7. Sister Sarah‏ @sarahdoingthing 19 Jan 2014
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      Replying to @St_Rev

      @St_Rev @DoTheWeirdStuff YES - oh man this fits into what we were talking about so well (Westermarck & wife trading as prerequisites)

      4 replies 0 retweets 0 likes
    8. St. Rev  ☯️ 🏴 😻‏ @St_Rev 19 Jan 2014
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      Replying to @sarahdoingthing

      @sarahdoingthing @DoTheWeirdStuff Trying to think of a good phrasing: gaussian-blurring the genome is selected for at species level.

      1 reply 0 retweets 1 like
      Sister Sarah‏ @sarahdoingthing 19 Jan 2014
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      Replying to @St_Rev

      @St_Rev @DoTheWeirdStuff I know what gaussian blurring is but I'm going to need more explanation here

      6:43 PM - 19 Jan 2014
      8 replies 0 retweets 0 likes
        1. New conversation
        2. St. Rev  ☯️ 🏴 😻‏ @St_Rev 19 Jan 2014
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          Replying to @sarahdoingthing

          @sarahdoingthing ...converge over time to a single optimal code. But that only applies if the environment is 100% predictable.

          1 reply 0 retweets 2 likes
        3. Sister Sarah‏ @sarahdoingthing 19 Jan 2014
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          Replying to @St_Rev

          @St_Rev we were just talking about variability - why do you think predictability determines this? (cool insight)

          6 replies 0 retweets 0 likes
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        2. St. Rev  ☯️ 🏴 😻‏ @St_Rev 19 Jan 2014
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          Replying to @sarahdoingthing

          @sarahdoingthing It seems like it would be hard have a 'mutate this gene but leave that one alone OK' mechanism. But who knows?

          1 reply 0 retweets 1 like
        3. David Chapman‏ @Meaningness 19 Jan 2014
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          @St_Rev @sarahdoingthing My recollection is that there are multiple mechanisms for adjusting mutability of parts of genome.

          2 replies 0 retweets 1 like
        4. 5 more replies
        1. St. Rev  ☯️ 🏴 😻‏ @St_Rev 19 Jan 2014
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          Replying to @sarahdoingthing

          @sarahdoingthing If there's variation in environment over time & space, the ability to maintain variation in genome is meta-selected for.

          0 replies 0 retweets 2 likes
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        1. St. Rev  ☯️ 🏴 😻‏ @St_Rev 19 Jan 2014
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          Replying to @sarahdoingthing

          @sarahdoingthing @DoTheWeirdStuff OK. Look at all the individual genomes of the members of a species. They form a sort of statistical cloud.

          0 replies 0 retweets 1 like
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        1. St. Rev  ☯️ 🏴 😻‏ @St_Rev 19 Jan 2014
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          Replying to @sarahdoingthing

          @sarahdoingthing i.e. the ideal strategy is a 'cloud' of separate variant strategies. This is especially seen with the MHC...

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        1. St. Rev  ☯️ 🏴 😻‏ @St_Rev 19 Jan 2014
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          Replying to @sarahdoingthing

          @sarahdoingthing ...less with strongly conserved genes. But variability itself, w/exception of MHC, is probably mostly a global property.

          0 replies 0 retweets 1 like
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        1. St. Rev  ☯️ 🏴 😻‏ @St_Rev 19 Jan 2014
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          Replying to @sarahdoingthing

          @sarahdoingthing On a first pass you might expect natural selection to force that variation to zero, so that all individual genomes...

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        1. St. Rev  ☯️ 🏴 😻‏ @St_Rev 19 Jan 2014
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          Replying to @sarahdoingthing

          @sarahdoingthing nb. In the bacteria study loss of DNA repair emerged quickly but regaining it was v. slow. Easier to deactivate a gene.

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