In response to the ongoing #COVID19 pandemic, we will deploy our large-scale genome sequencing platform, alongside regional sequencing centres, to better understand the coronavirus outbreak in the UK
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Wellcome Sanger Institute
@sangerinstitute
We are a world-leading genomics research centre. We undertake large-scale research that helps improve human health and understand life on Earth.
Wellcome Sanger Institute’s Tweets
We are deeply saddened to announce the death of Professor Sir John Sulston, founding director of the Wellcome Sanger Institute. He was a great scientific visionary and leader who made historic contributions to science.
The Earth BioGenome Project launches today – a historic mission to read the genetic code of 1.5 million known species of animals, plants, fungi & protozoa on Earth bit.ly/2OhnXQv
#EarthBioGenome #SequencingLife
#OTD Rosalind Franklin was born in 1920.
She is best known for producing Photograph 51, an X-ray image used by Watson & Crick to create their model of the structure of DNA.
Franklin’s work was unacknowledged at the time, but Crick later called her contribution critical.
#OnthisDay we celebrate the centenary of Fred Sanger - inventor of DNA sequencing, double Nobel Laureate & self-described ‘chap who messed about in the lab’. Read more on the father of genomics buff.ly/2wbJH9F
#OnThisDay Barbara McClintock was born in 1902.
She developed theories to explain the suppression and expression of genetic info from one generation of maize plants to the next. She is the only woman to receive an unshared Nobel Prize in Physiology or Medicine.
#WomenInSTEM
It's our anniversary! 🎉🎂
#OnThisDay 1993, the (then called) Sanger Centre opened, leading the UK contribution to the Human Genome Project 🧬
Warm wishes to all of our staff, collaborators and friends from the past 29 years
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🧬 The Sanger Institute was opened in 1992 to be a major contributor to the Human Genome Project.
#OTD 2000, the first draft was published, revolutionising biological research as we know it 🔬🧪🦠🧫
#HumanGenome20
Congratulations to Sarah Teichmann, who has been elected a Fellow of 🎉
Awarded for her contributions to computational biology and #genomics, including her role in founding
#RSFellows
It took us 25 years to read the same amount of DNA that we have been able to read in the past 12 months. Rapid technological advancements and the project have led to a huge acceleration in our data production
#10petabases #BigData
#OTD 1902 Barbara McClintock was born.
She won the for discovering that sections of #DNA can change position on a chromosome, affecting gene expression.
She is the only woman to receive an unshared Nobel Prize in Medicine.
#WomenInSTEM
The mission to map the genetic code of 66,000 UK species has begun. We are delighted to welcome Mark Blaxter to lead our new Tree of Life programme & Sanger’s contribution to the UK-wide Darwin Tree of Life Project.
#SequencingLife
Rosalind Franklin, pioneering chemist & X-ray crystallographer, was born #OnThisDay in 1920. She played a key role in solving the structure of #DNA, but died before knowing the true impact of her work. Read more on bit.ly/2OeNDOU
#WomeninSTEM
It's our birthday! 🎉🎂
#OnThisDay 1993, the (then called) Sanger Centre opened, leading the UK contribution to the Human Genome Project 🧬
Huge congratulations to Prof Matt Hurles ( ) who has been appointed as the new Director of ! 🎊
Currently Head of the Human Genetics Programme, Matt will formally take up the Directorship later this year.
Find out more⤵️
bit.ly/3Xq3T26
We were very sad to hear of the passing of our Honorary Faculty member Sydney Brenner, a giant figure in molecular biology.
Hear more about his life and work here:
"Scientific research is one of the most exciting and rewarding of occupations. It is like a voyage of discovery into unknown lands, seeking not for new territory but for new knowledge. It should appeal to those with a good sense of adventure."
Fred Sanger was born #OTD in 1918
As of 15:00 BST, all of our 17 NovaSeq sequencing machines are up and running, and we’re ramping up to sequence 10,000 whole genomes a month for the Whole Genome Sequencing Project.
#OTD 1920 Rosalind Franklin was born 👩🔬
Her research was critical to the discovery of the structure of DNA 🧬 though she received little recognition in her lifetime
Find out more about her life and work 👉 bit.ly/30BiRqk
#WomenInSTEM #Franklin100
From a teenage author 📙 to aiming to map every cell in the human body🧍Sarah Teichmann has had an inspirational career so far.
Read about our Head of Cellular Genetics on our blog ⬇️
#WomenInSTEM #HumanCellAtlas
CRISPR/Cas9 shown to cause more genome damage than thought. New study reveals caution is needed with potential #CRISPR gene therapies. bit.ly/2mmYz0h
15 years ago today, the draft human genome was completed. #anniversary #humangenomeproject yourgenome.org/stories/what-w
Genomics is set to become the biggest source of data on the planet, overtaking Twitter, YouTube, and astronomy. #Artificialintelligence and #machinelearning are helping researchers get the most from genomic data
bit.ly/2voRil4
Our sequencing labs are abuzz with excitement as first batch of human DNA samples arrive for #VanguardStudy. We will sequence whole genomes of 50,000 volunteers on tech to transform understanding of human #health.
Find out more: buff.ly/2vuCbpR
The Whole Genome Sequencing project will become a game-changing resource in understanding, diagnosis, treatment and prevention of life-changing diseases.
bit.ly/2kucapm
Babies born vaginally have their mother’s gut bacteria in their #microbiome, while babies born via caesarean do not. It’s unclear however what role this plays in future health and further study is needed
#MaternalHealth #GutBacteria #BabyBiome #Microbiota
bit.ly/2m226UB
With £9.4m from , the Sanger Institute & partners will launch the first phase of sequencing the genomes of all 60,000 species on the British Isles.
#DarwinTreeOfLife #BigData
30% of our scientific workforce come from outside the UK. Our science relies on international movement and collaboration.
#TogetherScienceCan #GlobalTalents #ScienceisGlobal
#OnThisDay Dorothy Crowfoot Hodgkin was born in 1910. She won the 1964 Nobel Prize in Chemistry, and determined the structures of penicillin, vitamin B12 and insulin. She remains the only British woman to have won a science Nobel Prize.
#WomenInSTEM
📢 Introducing the virtual Sanger Seminar Series! 📢 Hear from a member of our Faculty each month on their latest research.
First up, Sarah Teichmann! 🧫🧬🔬
📆 Weds 15 July, 4-5pm BST
🔗 More info 👉 bit.ly/3fdRZ5S
#SangerSeminars #ScienceTwitter #HumanCellAtlas
We are delighted to launch the Sanger Excellence #Postdoctoral Fellowship 👩🏿🔬👨🏿🔬🧑🏿🔬
Open exclusively to early-career researchers with a degree and PhD from a UK institution, and are from a Black heritage background
Find full info ➡️ sanger.ac.uk/news_item/laun
#BlackInSTEM
Congrats for the Gabor Medal for 25+ yrs developing genomics and computational biology bit.ly/2uEagG5
"One should not underestimate how important this event is in human history" – John Sulston
#OTD 1990, the Human Genome Project was officially launched 🧬
#HumanGenomeProject
#OTD 1920 Rosalind Franklin was born 👩🏻🔬
Her research was critical to the discovery of the structure of DNA 🧬 though she received little recognition in her lifetime
Find out more about her life and work ➡️ bit.ly/30BiRqk
#WomenInSTEM
#OTD 20 years ago the #HumanGenomeProject was completed, revolutionising the field of #genetics 🧬
Today, we continue to build upon this incredible achievement, exploring new ways to use genetic information to improve human #health.
19% of our staff are from the EU, and 24% of our scientific and technical staff are from the EU. We could not do the work that we do without these invaluable people.
#TogetherScienceCan #Brexit
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On being asked if an institute could be named after him, Fred Sanger replied "it had better be good". We celebrated the centenary of Fred Sanger this year, and hope we have made you proud
#HoHoHighlights
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#OnthisDay we celebrate the centenary of Fred Sanger - inventor of DNA sequencing, double Nobel Laureate & self-described ‘chap who messed about in the lab’. Read more on the father of genomics @yourgenome buff.ly/2wbJH9F
We stand with our staff, collaborators, and friends around the world in condemning racism and discrimination. We’ve still got work to do, and we are committed to doing it.
#BlackLivesMatter #BlackInSTEM
Sanger International Fellow began her scientific career milking scorpions to study anti-venoms 🦂
Now, she is a PI , studying #AcralMelanoma, the most common #Melanoma in parts of Latin America, Asia, and Africa 🔬👩🏻🔬
sangerinstitute.blog/2021/03/16/fro
Applications for the Sanger Prize are now open! This prize gives LMIC undergrad students the opportunity to work in one of our labs for three months, all expenses paid 🏅🧪🔬🥼
📅 Deadline 11 December
Full info on how to apply 👉 sanger.ac.uk/about/the-sang
#SciencePrize #Funding
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As we look back on this year, we would like to take a moment to once again remember Prof Sir John Sulston, who passed away in March. We owe a huge amount to John, and can only thank him for his contributions to Sanger, and science as a whole
We are firing up NovaSeqs to read the first of 50,000 human genomes for #VanguardStudy. Excited for the data to start streaming out! #BigData #Health #Research
For more info: buff.ly/2vuCbpR
Congratulations to Sarah Teichmann and the UK team for this funding for #HumanCellAtlas data collection! #BigData
buff.ly/2vV33iU
Congratulations to 🎉 who has received funding to study the human immune response to #COVID19 and the progression of the disease 🔬
sanger.ac.uk/news/view/sang
Today is #RosalindFranklin's birthday - one of the Giants in #Genomics. Find out more about the 'Dark Lady of #DNA' bit.ly/1SK0O9M
February is #LGBTHistoryMonth, and we are #proud to celebrate the importance of #inclusivediversity in science
#LGBTHM19 #PrideInSTEM
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We are pleased to announce that the #genomes of the European robin and Turtle dove have been sequenced and assembled for the first time
#25Genomes
Congratulations to , our Head of Human Genetics, who has been elected as a Fellow of the .
#HumanGenetics #Genomics #DecipheringDevelopmentalDisorders #RoyalSociety
bit.ly/2InNAk9
We are delighted to sequence the full #genomes of 50,000 volunteer participants to help transform research into a wide range of diseases. bit.ly/2H3vq6b
We’ve now sequenced more than 5 Petabases of DNA. If you strung all the 5,000,000,000,000,000 #DNA bases together that our sequencing machines have read, then the result would be out of this world. #5petabases
The first human #pangenome has been published🧬
This important work better captures genetic variation and diversity.
Find out more in our latest blog ⬇️
Sex matters in #AnimalResearch.
Scientists & found the differences between ♂️ & ♀️ mice affect research results.
Our staff continue to improve design of animal studies ➡️ bit.ly/2LXoklL
#AnimalStats
The developing human lung has been mapped in unprecedented detail, identifying 144 cell types in the early stages of life
Acting as a guidebook to healthy lung development, this can be used to investigate how #lungdiseases originate
Read more 👇🏻
bit.ly/3P8C9MQ
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#OTD 1918 Fred Sanger was born 👨🔬
Known as the “father of #genomics”, when John Sulston asked if he could name the institute after him, Fred replied “it had better be good” ✨
Read more about Fred’s life and work 👉 bit.ly/3iwrji8
Time flies when you work in #genomics. Sequencing DNA used to take years, now it takes minutes.
#10petabases #BigData
Congratulations to Sarah Teichmann, awarded the 2018 Mary Lyon Medal for outstanding research, using #genomics and #bioinformatics to understand the #immune system. bit.ly/2noVZXB
#OTD 2003 the Human Genome Project was completed - a global project that was the foundation of our institute
Did you know that sequencing the #genomes of all 1.5 million known #eukaryotes will cost less than the Human Genome Project did?
is a Science Writer in our Comms Team
#WednesdayWisdom
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Congratulations to everyone & on sequencing 100,000 genomes with ! This is a huge achievement and will make a massive impact on improving results for patients #100KThankYous #Genomes100k
bit.ly/2Qj1hW3
Congratulations and on your election as Fellows to for your research into how the human #genome influences risk of common diseases and how genes drive #cancer bit.ly/2rvXW7y
We recruit talented scientists and software developers from around the world to deliver our science and make the UK a global leader in genomics. We need an immigration system that allows us to recruit the best and brightest.
The #Finalfive species for our #25genomes project have been decided by the public vote! They are: Lesser Spotted #Catshark, Common #Starfish, Asian #Hornet, Fen Raft #Spider and Eurasian #Otter
For the full list of #species: bit.ly/2kDnaQO
@WGCengage
Researchers have created a new two-stage saliva test for #SARSCoV2 that is simpler and easier to use than nasal swab tests 🧪😷
“Having more women as thought leaders in science will diversify the qualities on which we judge excellence”
👋 on her life and career, in this week’s
#WomenInSTEM #AcademicTwitter
Providing new insights into how blood and immune systems develop in the first 17 weeks in utero, scientists have created the human developmental liver cell atlas
#HumanCellAtlas #StemCells
bit.ly/30X24fD
Roses are red
Violets are blue
Did you know 2000 #bacteria
Were found in your poo? 💩
#AcademicValentine #ValentinesDay
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Nearly 2000 uncultured #bacteria in the human gut have been discovered. The team used #computational methods to analyse samples from people worldwide, to help understand role of #microbiome in human health.
@LawleyLab @emblebi #metagenomics #gutbacteria
bit.ly/2SyU4lR
The Sanger Prize offers undergrads from low and middle-income countries the chance to spend 3 months with a research group at the Sanger Institute, with travel, living and research expenses covered. Find out how to apply for our 2019 Prize #SciencePrize
bit.ly/2D8UOoK
The Sanger Institute has read 10,000,000,000,000,000 bases of DNA since we opened in 1993
#10petabases #BigData #DNA
It’s #AdaLovelaceDay! We asked some of our software developers and bioinformaticians which #WomenInTech inspired them 👩🏻🔬👩🏽🔬👩🏿🔬
Find out who they said on our blog ⬇️
sangerinstitute.blog/2019/10/08/pio
🧬 Determining the order of four letters of DNA has transformed how we understand life on Earth 🌍
We’re reflecting on what followed the Human Genome Project for the Sanger Institute, and what the future holds 🔮
#HumanGenome20
We are delighted that Alan Turing and his science will be celebrated as the new face of the £50 note.
We were also thrilled that our namesake Fred Sanger was shortlisted for this honour, for his pioneering contributions to our understanding of genetics
#ThinkScience
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Introducing the face of the new £50 note - the father of computer science, Alan Turing.” Find out more bankofengland.co.uk/thinkscience #Turing50 #ThinkScience
We are thrilled to be part of the Whole Genome Sequencing collaboration to sequence 500,000 human genomes, powering the next wave of genetic and health research
#HoHoHighlights #Genomics
By resurrecting a 50,000-year-old gene sequence, scientists have uncovered how the world’s deadliest #malaria parasite jumped from gorillas to humans
#Plasmodium
It’s our 25th #birthday in 2018 & we’re sequencing #25genomes. Working with & others! bit.ly/2Aopfnh
Cancer is, at its core, a genomic disease. The hunt for the precise DNA changes that turn a healthy cell into a cancerous one has led to new understanding and new treatments.
#CancerGenomics #BigData
As a sequencing hub for the national effort, we’re often asked how many #SARSCoV2 genomes we sequence. These are the numbers, as of this week ⤵️
Check out our blog for more info on the data ➡️ sangerinstitute.blog/2021/02/05/seq
#COVID19
Dr Sarah Teichmann () has received the | Women in Science Award 2023 for her outstanding achievements and for inspiring future generations of #womenandgirlsinSTEM
Read the full story ⤵️
#womeninscience #WellcomeGenomeWomen
We’ve just read our 5,000,000,000,000,000th base. In fact, by the time you’ve finished reading this sentence, our sequencing machines will have read another 273 million #DNA bases. #5petabases
Today we celebrate our 26th anniversary! Many congratulations and thanks to all of our staff, collaborators and friends from the past 26 years.
Here’s to the next 26!
GIF
Today marks the next chapter in the UK’s relationship with Europe. Whatever the outcome of Brexit, we will remain open and welcoming to scientists and students from around the world.
#ScienceIsGlobal #Brexit
sanger.ac.uk/news/view/brex
Today is the 2nd International #LGBTSTEMDay! We’re proud to support and celebrate the LGBT community in STEM, and recognise the work still to be done.
#Pride
Ancient #DNA & Human #Evolution – latest BBC Inside Science with at #HumanEvol17 features Svante Pääbo & other scientists who use DNA to study our #ancestors.
buff.ly/2CEtfBl @WGCengage
#Sequencing the #DNA of 1.5 million species - all known animals, plants, fungi & protozoa on Earth - is estimated to cost $4.7bn. This is less than the cost (in today's money) that it took to sequence just one human genome. #EarthBioGenome #SequencingLife
bit.ly/2OnNwiO
Researchers used #CRISPR to uncover #GeneFusions that are critical for the growth of cancer cells & found a new drug target for multiple cancer types.
#GeneFusion #CancerResearch #DepMap
bit.ly/2EcN7Ob
As a sequencing hub for the national effort, we’re often asked how many #SARSCoV2 genomes we sequence. These are the numbers, as of this week 🧬⤵️
Check out our blog for more info on the data ➡️ sangerinstitute.blog/2021/02/05/seq
#COVID19
Genomics is set to become the biggest source of data on the planet, overtaking Twitter, YouTube, and astronomy. #ArtificialIntelligence and #MachineLearning are helping researchers get the most from genomic data
We are proud to be part of #EarthBiogenome project with a goal to sequence 66,000 UK species’ genomes with our partners
buff.ly/2zirtVd #SequencingLife
#Organoids are clusters of cells that resemble miniature organs and are becoming commonplace in research, giving researchers a way to mimic how conditions such as cancer and #CysticFibrosis affect cells.
Learn more on our blog ⬇️
Government proposals to increase the immigration health surcharge will have a detrimental impact on UK & global science.
International collaboration is vital for research and innovation.
The UK has one of the most expensive immigration systems globally, putting science at risk.
We were delighted this year to partner with to provide whole-genome sequences for 50,000 volunteer participants, funded by . Read more on how this will contribute to health research: bit.ly/2ErfVDl
#BigData
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We are firing up @illumina NovaSeqs @sangerinstitute to read the first of 50,000 human genomes for @UK_Biobank #VanguardStudy. Excited for the data to start streaming out! #BigData #Health #Research
For more info: buff.ly/2vuCbpR
This year, we read our 10th petabase of DNA since we opened in 1993 🧬 It took 12 months to read the same amount that had been read in the previous 25 years
#HoHoHighlights #10petabases
We are delighted to welcome Prof Ben Lehner to this week
He joins the Human Genetics Programme & will be using high-throughput experiments and AI to lay the foundations for programmable biology and protein engineering
Find out more ⬇️
More than 250,000 single cells have been studied to reveal how gene activity shapes the innate immune system. Research charts the evolution of antiviral and antibacterial #immunity. #genomics bit.ly/2z2a8Qi
GIF
🧬 Determining the order of four letters of DNA has transformed how we understand life on Earth 🌍
20 years after publication, we're reflecting on what followed the Human Genome Project for , and what the future holds 🔮
#HumanGenome20