Their research demonstrates immune response to B.1.351 is as potent as that seen in those infected with the original variant. Furthermore, antibodies from people infected with B.1.351 are not only able to neutralize B.1.351 but variant P.1 as well!
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The press conference can be found here:https://www.youtube.com/watch?v=N5zPxr-2X44 …
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Remember, TCRs play a huge role in disease resolution and modulation of COVID-19 disease severity. While they may not protect you from a mild/moderate infection, they can however proliferate rapidly and prevent the build up of viral load-
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which in turn drives disease severity, therefore preventing severe cases and helping us stay out of the hospital. In addition, TCRs ensure and solidify the ability of our immune systems to make sure it can produce an adequate response the next time it comes into contact with the
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the virus. Our T-cells recognize different regions of the Coronavirus’ spike protein compared to the neutralizing antibodies produced by our B-cells from vaccination and/or natural infection. This implies they will be more resilient to these AND future variants. Let me explain:pic.twitter.com/XPJXXJiK8S
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Should you still get vaccinated? ABSOLUTELY. These vaccines will help further boost these robust TCR immune responses (all the while protecting you) and that’s the cherry on top.
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Full preprint: the observed effective neutralization of first wave virus by 501Y.V2 infection elicited plasma provides preliminary evidence that vaccines based on VOC sequences could retain activity against other circulating SARS-CoV-2 lineages. https://www.medrxiv.org/content/10.1101/2021.01.26.21250224v2 …
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Amazing news Chise, just so I'm grasping this...basic level - If you've had covid and recovered your antibodies are very likely to protect you from all variants, or at least all current VOCs?
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Can we hope this works the other way round as well? And infection/vaccination against the original or Kent variant will provide cover against the SA or Brazil variant?
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I assume that that sera from the patients infected with B.1.351 should have no problem neutralizing B.1.1.7 as it does not have immune evading capabilities
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That’s exactly what I am thinking. ;3
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