Improving performance on learning mazes in aged rats is also not unique.
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It looks interesting as a potential broad-spectrum effect from a complex multi-compound extract, but it would strengthen the case of the authors if they were to include more metrics-- telomere length, more data on senescent burden, ideally average and maximum lifespan, etc.
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Effects on connective tissue would also be useful to understand. Any given metric can be criticized, including these ones, but a combination of sufficiently many disparate indicators of benefit close to core mechanisms of the aging process would be more compelling.
End of conversation
New conversation -
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Yup, I had the exact same thought. Basically, epigenetic clocks correlated well with age and various health indicators in certain settings. However, what percentage of *interventions* that turn back epigenetic clock actually improve longevity? It's not a trivial question
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