3.) and 4.) low lung weight and recruitability: only a small amount of lung tissue is damaged (and thus filled with liquid or "recruitable" by forcing the alveoli open with ventilatory pressure).
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The big conclusion the COVID19 paper draws about patients with low oxygen but no dyspnea is *give 'em lots of oxygen.* Tradeoffs are more ambiguous about PEEP.
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The other conclusion is that you want to intubate when the inspiratory pressure swings are starting to get big, as controlling the breathing rate can *prevent* additional lung injury.
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"As esophageal pressure swings increase from 5 to 10 cmH2O—which are generally well tolerated—to above 15 cmH2O, the risk of lung injury increases and therefore intubation should be performed as soon as possible."
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Also, if we could figure out *how* COVID19 blocks hypoxic vasoconstriction, and find a way to make it *stop*, those "silent hypoxemic" patients could get their V/Q back to normal, and thus would no longer be hypoxemic (since they don't have much lung damage to begin with.)
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As a non-medical person... Would this also recommend starting oxygen earlier in treatment, and at higher flow rates? Adjust oxygen flow to maintain normal breathing rate?
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it sounds like it? but i'm not entirely sure, still learning
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