As it turns out, this isn't just a thought experiment. The Kefauver-Harris Amendments required evidence of drug efficacy for the 1st time, and required the NAM to review older drugs for efficacy. Half the marketed drugs in the US were withdrawn as a result.https://twitter.com/s_r_constantin/status/1258043966051643398 …
The question is, do they also sell more *effective* drugs? And which is larger, the benefit from effective drugs or the harm from ineffective ones?