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s_r_constantin's profile
Sarah Constantin
Sarah Constantin
Sarah Constantin
@s_r_constantin

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Sarah Constantin

@s_r_constantin

Math/ML/data-science person now working on solving aging...and helping with COVID19?! Founder, LRI and Daphnia Labs. Married to @oscredwin

Be
srconstantin.posthaven.com
Joined February 2019

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    Sarah Constantin‏ @s_r_constantin May 4
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    New blogpost: silent hypoxemia in #COVID19 and avoiding intubation. It's not just podcasts and Twitter threads any more: we have published papers calling for early & abundant O2, awake proning, and CPAP in silent-hypoxemic COVID-19 patients.https://srconstantin.github.io/2020/05/04/silent-hypoxemia.html …

    1:48 PM - 4 May 2020
    • 21 Retweets
    • 51 Likes
    • Molly Gordon Rogs says test everyone alice maz __, (25 second attention span) QC Adam Strandberg Venkatesh Rao Linked Out Seb Insua
    6 replies 21 retweets 51 likes
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      2. Sarah Constantin‏ @s_r_constantin May 4
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        Italian ICU that uses helmet CPAP as first-line for severe COVID-19 has half the death rate of US ICU (in Seattle) that uses invasive mechanical ventilation for all severe cases. 24% vs 50%. Similar disease severity at admission.

        2 replies 5 retweets 22 likes
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      3. Sarah Constantin‏ @s_r_constantin May 4
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        Simple suggestion by NYC emergency physician Richard Levitan: get a pulse oximeter at the drug store. Check yourself BEFORE you have trouble breathing. If people with asymptomatic hypoxemia get prompt oxygen therapy, they might never progress to severe disease.

        2 replies 8 retweets 27 likes
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      4. End of conversation
      1. Kevin Marks‏ @kevinmarks May 4
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        Replying to @s_r_constantin

        Another report that matches this from an ICU doctor in the UKhttps://www.nomoresurgeons.com/post/wishful-thinking …

        0 replies 0 retweets 2 likes
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      2. Nerwen‏ @Cererean May 5
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        Replying to @s_r_constantin

        This is what happens when you abandon evidence based medicine and rush to build ventilators. We should have required Randomised Controlled Trials to prove ventilation helps, as we do for Hydroxychloroquine.

        1 reply 0 retweets 0 likes
      3. Sarah Constantin‏ @s_r_constantin May 5
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        Replying to @Cererean

        fwiw the group I was working with *is* building CPAP/BiPAP machines, not ventilators.

        0 replies 0 retweets 1 like
      4. End of conversation
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      1. Invert Avian‏ @Invert_Avian May 4
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        Replying to @s_r_constantin

        Weeks ago I got a chain-y “COVID tips!” email with the claim that a home diagnostic is to try and hold your breath for ten seconds, and that difficulty doing so is a sign of COVID. If happy hypoxics are compensating for reduced lung function, maybe this actually works(ish)?

        0 replies 0 retweets 0 likes
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      1. : : :‏ @UgaritNoosphere May 4
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        Replying to @s_r_constantin

        @whitechoco8533

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