New lit review post, this one on #COVID19 antibody testing.https://srconstantin.github.io/2020/04/27/antibody-testing.html …
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As a guide to clinical treatment of individual patients? Probably not great, since they'll show up negative even in infected patients for the first two weeks after symptom onset.
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As a guide to identifying who needs to be quarantined? Again, not ideal, because they'll miss newly infected patients (who are at their most contagious) but maybe better than nothing.
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My general heuristic of "don't trust claims by known COVID-19 Pollyannas" seems pretty vindicated by the facts here.
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The problem is that antibodies aren't completely selective to a single target, so you get false positives. And current tests have a significant and not-really-known false positive rate. So unfortunately, we just don't know.
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Already priced into my calculations
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nitpick — the study I immediately wanted to look up was the one with a missing citation! (47, on human coronavirus precedent)
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fixed, thanks. Callow, Kathleen A. "Effect of specific humoral immunity and some non-specific factors on resistance of volunteers to respiratory coronavirus infection." Epidemiology & Infection 95.1 (1985): 173-189.
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