the "H-type" COVID19 patient is more classic ARDS with poor lung compliance & alveolar collapse. Patients often come in as L-type, some get well, some progress to H-type.
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should we be worried about giving people hardcore immunosuppressants when they have an infectious disease? well you do NOT want to be giving tocilizumab to anyone with mild disease where their immune system might fight it off.
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do you want to be neutropenic when you're fighting off a virus? you do NOT. L-type patients or milder? not good candidates for tocilizumab.
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is opening up the country with no adequate antibody testing, no prophylactic treatment, no vaccine, and not even knowledge of how long immunity lasts, a good idea? NOPE, says doc.
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for heart problems in COVID19: you can't tell myocarditis from STEMI from EKG alone, "take 'em to the cath lab" (ie heart biopsy) because you treat these conditions very differently.
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scary thing: the EDs aren't seeing their usual *non* COVID19 cases, their heart attacks and strokes and DKAs, because telling everybody to stay home has worked so well. people are showing up to their GP's office with these emergency conditions.
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apparently trying to resuscitate after a non-shockable cardiac arrest has a very poor success rate and can aerosolize the virus, so they're telling people *not* to do chest compressions in COVID19 patients.
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(they recommend talking to your patients about end-of-life plans beforehand, and reciprocally it seems like PATIENTS should think about their end-of-life wishes because I can see a lot of people being very disturbed by finding out that the default is not to resuscitate!)
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management of cytokine release syndrome as an AE of CAR T therapy is basically routine now, even though it’s an ICU side effect; toci in this context isn’t all that arcane
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good to know! thanks!!
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