You know how hypothalamic function declines with age? This paper seems to isolate an essential mechanism for that, and shows that it can be reversed. (In mice, of course.)https://twitter.com/aginghighlights/status/1222965066850603009 …
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OTOH we know that humans don't have *all* the long-life switches turned on, because there are animals that live longer than us (some tortoises & whales) and animals that don't get cancer (elephants) or senescence at all (naked mole rats).
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Or even our senescent cells could be more nicely behaved (like in Spalax, a naked mole rat cousin that seems to have a very mild SASP)
End of conversation
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