Possible irrationality in biomedical research: small-N human studies get derided as “too small, preliminary” even if the effect is clear and consistent enough to have a low p-value; animal studies often use tiny numbers of animals or don’t even list the number.
Mostly medicine. Like, minocycline for schizophrenia is iirc an example where the effect is big enough despite the small study size that dismissing it because “too small” seemed wrong. Especially since multiple comparisons didn’t apply; it was an accidental discovery.
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One could check this empirically. Look at results from small studies that were deemed sufficiently powered and check effect size in bigger follow up studies.
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