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s_r_constantin's profile
Sarah Constantin
Sarah Constantin
Sarah Constantin
@s_r_constantin

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Sarah Constantin

@s_r_constantin

Math/ML/data-science person now working on solving aging...and helping with COVID19?! Founder, LRI and Daphnia Labs. Married to @oscredwin

Be
srconstantin.posthaven.com
Joined February 2019

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    1. Sarah Constantin‏ @s_r_constantin 16 Oct 2019
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      Sarah Constantin Retweeted

      "The problem with insulin costs is that the government will shoot anyone who tries to make cheap insulin." https://t.co/hmVWCTuT3V 

      Sarah Constantin added,

      This Tweet is unavailable.
      5 replies 19 retweets 58 likes
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    2. ЬᏂ​au​ϮᏂ‏ @peroxycarbonate 16 Oct 2019
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      Replying to @s_r_constantin

      > the median approval time did not significantly decline > increase in approved drugs was largely driven by approvals of the fourth, fifth, sixth versions of genericshttps://www.pewtrusts.org/en/research-and-analysis/issue-briefs/2019/02/fda-approves-more-generic-drugs-but-competition-still-lags …

      1 reply 0 retweets 2 likes
    3. ЬᏂ​au​ϮᏂ‏ @peroxycarbonate 16 Oct 2019
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      Replying to @peroxycarbonate @s_r_constantin

      > Before GDUFA (see fiscal 2012), the median approval time was 31.75 months, but median approval time was 36 months in fiscal 2013. Median approval time increased to 42 months in fiscal 2014 and 2015 before declining to 39.42 months in 2016 and 37.26 months in 2017.

      1 reply 0 retweets 1 like
    4. ЬᏂ​au​ϮᏂ‏ @peroxycarbonate 16 Oct 2019
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      Replying to @peroxycarbonate @s_r_constantin

      Now, I'm not sure exactly what you're proposing Sarah. Do you think drug manufacturer's shouldn't need FDA inspections? That's a hard sell. Do you think the FDA needs more money for inspectors? Congress could do that, if it thought that would win elections.

      1 reply 0 retweets 1 like
    5. ЬᏂ​au​ϮᏂ‏ @peroxycarbonate 16 Oct 2019
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      Replying to @peroxycarbonate @s_r_constantin

      Maybe no fees for drugs not currently being made? But then you have a new review process taking 3 years, before the drugs get made. Maybe the problem is the review process taking 3 years. But how, exactly, are you going to fix that?

      1 reply 0 retweets 1 like
    6. Sarah Constantin‏ @s_r_constantin 16 Oct 2019
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      Replying to @peroxycarbonate

      Oh, I'm too radical to have any intuition at all what kinds of incremental policy are within the Overton Window. (@bkavoussi?)

      2 replies 0 retweets 2 likes
    7. ЬᏂ​au​ϮᏂ‏ @peroxycarbonate 16 Oct 2019
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      Replying to @s_r_constantin

      What's your radical solution, then? Just let consumers decide? Consumers don't *want* to decide that, and it's unreasonable to ask individuals to do what the FDA has trouble with. Plus, many people say, "if it was really bad, it would be banned".

      2 replies 0 retweets 1 like
    8. Emma  😷‏ @geekethics 16 Oct 2019
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      Replying to @peroxycarbonate @s_r_constantin

      Nobody wants to decide that. But I think many people, currently faced with the choice "or death", would like the choice "take this dodgy untested thing or death".

      1 reply 0 retweets 0 likes
      Sarah Constantin‏ @s_r_constantin 16 Oct 2019
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      Replying to @geekethics @peroxycarbonate

      We are already taking dodgy untested things; the FDA isn't even that good at guaranteeing purity. Conversely, you can have a non-FDA service that tests drug purity.

      9:50 AM - 16 Oct 2019
      1 reply 0 retweets 0 likes
        1. New conversation
        2. Emma  😷‏ @geekethics 16 Oct 2019
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          Replying to @s_r_constantin @peroxycarbonate

          Oh of course. As always with healthcare "safety" is compared to perfection and not to current reality. But even if we assumed the FDA were currently producing perfect safety, we'd still have a problem.

          1 reply 1 retweet 1 like
        3. ЬᏂ​au​ϮᏂ‏ @peroxycarbonate 16 Oct 2019
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          Replying to @geekethics @s_r_constantin

          There are multiple places near me that sell things like saline IVs to people, for health reasons. I know some old people who are getting a scam stem cell therapy for pain, who were told their insurance would pay for it but those claims will get rejected and they'll be liable.

          1 reply 0 retweets 1 like
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