http://jpet.aspetjournals.org/content/jpet/371/1/1.full.pdf … This is big news; an antipsychotic that's NOT a D2 agonist.
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So they try many drugs on mice in the SmartCube, to see if a small % of them match? Thinking it must be hard to screen discover drugs with novel mechanisms of action.
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Yes. I think they must have some intelligent preselection process or else it would be hugely inefficient.
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