There are tons of rodent studies showing that various compounds have “neuroprotective” effects: that is, if you damage the brain by hypoxia or blunt force trauma, the animal’s cognitive function recovers better if you administer a drug right after injury.
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Guesses: a.) brains are hard; b.) most human TBI patients are old, whereas mouse models of TBI aren’t; c.) in real life people don’t get treated *immediately* after a head injury or stroke, whereas lab mice with experimentally-induced injuries are
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I have no expertise here, but the mouse genome induces senescence within a couple years, while the same neurons have to last for many decades in humans. Mice should have much more leeway in increasing recovery and longevity, and easier routes to activate them.
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Unless the study had been replicated in another group I'd wager it's more due to publication bias.
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