https://www.statnews.com/2019/08/01/rotifer-unsung-invertebrate-teaching-us-about-aging/?fbclid=IwAR2ZK1QeUqQ3JAfl50mtLh_-JNK4pd1Jllwsw5KW9xpcX8kyT2C6sWL3zi8 … Rotifers: another invertebrate model organism for aging. Like Daphnia, their phototactic response declines with age.
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A melatonin-like indole https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0010206 … by 300%: similar molecules have been found to extend life in worms, flies, and mice
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Rapamycin, by 37% (also extends life in worms, flies, and mice):https://www.sciencedirect.com/science/article/pii/S0531556514000345 …
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total darkness or short photoperiods (by 22% and 18%; photoperiod affects lifespan in Drosophila too but direction of effect varies with strain);https://www.sciencedirect.com/science/article/pii/053155658490007X …
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Glycerol ( a CR mimetic) and 2-deoxyglucose (a glycolysis inhibitor). https://www.sciencedirect.com/science/article/pii/S0531556514001442 … 2DG also extends life in nematodes but causes increased mortality in rats.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2830378/ …
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