Brokenness = potential energy. Anything badly broken is a dam holding back a lake of unrealized desires. A startup that can bore a hole through such a dam can liberate all that energy.
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My bias is that scientific problems (how to prevent disease without difficult lifestyle changes) are easier to solve than organizational ones (how to make medical care affordable), but both types of solutions are worth trying.
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Preventing disease will reduce some costs for sure. For example, the estimate is that about $800B is spent worldwide per annum on Alzheimers. An actual cure would thus have a net present value of about $20Trilion, an astonishing sum.
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